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Bioinformatics, biostatistics and information systems (Bio2SI)

General description

The Bioinformatics, Biostatistics, and Informatics and Information Systems Platform of the IIS Biobizkaia provides cross-disciplinary scientific and technological support to the institute's research groups, facilitating the management, analysis, and interpretation of complex biomedical data. Its main objective is to promote excellent research through advanced computational analysis tools, methodological advice, and IT solutions tailored to the needs of each project.

This platform integrates specialized knowledge in three complementary fields (bioinformatics, biostatistics, and information systems) allowing a comprehensive approach to the challenges posed by modern biomedical research. Through a collaborative approach, it promotes efficient data management, quality analysis, and technological innovation at the IIS Biobizkaia.

Activities and services

These are the activities carried out by the platform and services that the platform performs:

Bioinformatics

  • Gene Expression Analysis.
  • Single-Cell Analysis.
  • Variant calling, annotation and prioritisation.
  • GWAS analysis.
  • Epigenetics Analysis.
  • Proteomics and metabolomics Analysis.
  • Data integration and systems biology.

Biostatistics

  • Collaboration in the design of databases.
  • Creation of statistical plans, design adaptation strategy and intermediate analysis, and in general application of tools to optimize project efficiency.
  • Debugging, data processing and design of statistical analysis plans. Will develop statistical analyzes and interpretation of results.
  • Calculation of sample size.
  • Creating randomization lists.

Computing and information systems

  • Design and development of the information structure of the Institute and selection of the necessary software. Design, development and maintenance of the institute's website.
  • Review and update of the contents of the Institute's website, always in contact with its authors.
  • Management of Linux and Windows operating systems. Management of eventual computer access to visiting researchers on their own computers and / or on Biobizkaia Institute computers, including access to the Internet, email, as well as printing / scanning services.
  • Technical advice on computer applications and equipment: request for offers, preparation of reports and selection proposal in collaboration with other agents involved.
  • Computer equipment and applications configuration: configure and install new computer equipment / applications.
  • Management of user incidents and interrelation with the center's IT services.
  • Design of data collection sheets (paper).
  • Database design: Advice on the DB design phase (selection and coding of variables, structuring and relationships of the data, selection of the data manager sw, etc.).
  • Development of complete local database: Implementation of functionalities for its exploitation, consultation, debugging, quality control, etc.
  • Preparation of data for exploitation and analysis: processes of consultation, validation, debugging and export to statistical programs.
  • Technical Project Office: Technical advice and dialogue for projects developed by external companies (identification of needs, monitoring of execution, etc.).

Infrastructures

Currently, the Bioinformatics, Biostatistics and Information Systems Platform (Bio2SI) has the following infrastructure:

High process computer (HPC)

HPC Izaro

The compute cluster consists of the following features:

  • 1 X430 A6 management node. 1 AMD Turin 9655 processor with 96 cores at 2.6GHz. 128 GB of RAM and two 0.96 TB SSDs.
  • 3 Thin Bull Sequana X440 A6 compute nodes. Each with two AMD Turin 9655 processors with 96 cores at 2.6GHz. 1152 GB of RAM (6 GB per core) and two 0.96 TB SSDs.
  • 2 Fat Bull Sequana X430 A6 compute nodes. Each with one AMD Turin 9655 processor with 96 cores at 2.6GHz. 1152 GB of RAM (12 GB per core) and two 0.96 TB SSDs.
  • 1 Bull Sequana X450 A6 GPU compute node. 1 Nvidia L40S. 1 AMD Turin 9655 processor with 96 cores at 2.6 GHz. 1152 GB of RAM (6 GB per core) and two 0.96 TB SSDs.
  • High-performance storage system with 830 TB net capacity in Beegfs-type scratch. The storage servers are two Bull Sequana X430 A6, each with one AMD Turin 9655 processor with 96 cores at 2.6 GHz. 128 GB of RAM and two 0.96 TB SSDs.
  • 220 TB cold storage system.

More information

Contact forms

Account request for the use of HPC Izaro

Contact form - Bioinformatics

Contact form - Biostatistics

Contact form - Informatics and information systems

Platform members

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