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Biomarcadores en cáncer

Biomarcadores en cáncer

Líneas de investigación

Estudio de sistemas peptídicos en cáncer
Fosfatasas y quinasas como biomarcadores y dianas terapéuticas en cáncer
Estudios genotipo-fenotipo de fosfatasas involucradas en cáncer hereditario

Foto grupo

Coordinador/a del grupo



Miembros del grupo

  María Salomé Álvarez Sánchez
 
 
  Goikoane Cancho Galán
 
 
  María del Carmen Etxezarraga Zuluaga
 
 
  Pedro Francisco García Alonso
 
 
  Gorka Larrinaga Enbeitia
 
  Alberto Loizate Totorikagüena
 
  José Ignacio López Fernández de Villaverde
 
 
  Noelia Morales Boiza
 
 
  Amparo Pérez Fernández
 
 
  Itxaro Pérez Urzelai
 
  Jon Danel Solano Iturri
 
 
  Elvira Acebo Mariñas
 
 
  Aintzane Apraiz García
 
  Aintzane Asumendi Mallea
 
  María Dolores Boyano López
 
  José Luis Díaz Ramon
 
 
  Ana Sánchez Díez
 
 
  María del Rosario Fátima González Hermosa
 
 
  Rosa María Izu Belloso
 
 
  Gorka Pérez-Yarza Pérez-Irezabal
 
  Juan Antonio Ratón Nieto
 
 
  Peru Urigoitia Ugalde
 
 
  Veronica Velasco Benito
 
 
  Mónica Saiz Camín
 
 
  Marc Julia Manresa
 
 
  María Isabel Idigoras Rubio
 
 
  María Isabel Portillo Villares
 
 
  Isabel Bilbao Iturribarria
 
 
  Cristina Penas Lago
 
 
  Fidencio Bao Pérez
 
 
  Maider Pretel Irazabal
 
 
  Aintzane Goya Mendiluce
 
 
  Pedro Coterón Ochoa
 
 
  Ane Miren Iturregui Del Pozo
 
 
  Cristina Penas Lago
 
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  Irati Allende Markixana
 
 
  Ainhoa Alonso Pardavila
 
 
  Jorge Francisco González Tampan
 
 
  Victoria Morillo Montañes
 
 
  Izaskun Ocerin Guerra
 
 
  Maria Riaza Montes
 
 

Publicaciones del grupo

Manini C, Lopez JI. Pathology and the evolutionary dynamics of clear cell renal cell carcinoma. Transl Oncol. 2023; 27: 101601-101601. DOI:10.1016/j.tranon.2022.101601.

Malaina I, Martinez L, Montoya JM, Alonso S, Boyano MD, Asumendi A, et al. A Universal Antigen-Ranking Method to Design Personalized Vaccines Targeting Neoantigens against Melanoma. Life-Basel. 2023; 13(1). DOI:10.3390/life13010155.

Martin Saiz L, Abad Garcia B, Solano Iturri JD, Mosteiro L, Martin Allende J, Rueda Y, et al. Using the Synergy between HPLC-MS and MALDI-MS Imaging to Explore the Lipidomics of Clear Cell Renal Cell Carcinoma. Anal Chem. 2023; 95(4): 2285-2293. DOI:10.1021/acs.analchem.2c03953.

Manini C, Provenza C, Andrés L, Imaz I, Guarch R, Nunziata R, et al. Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation. Clin Pract. 2023; 13(1): 288-296. DOI:10.3390/clinpract13010026.

Manini C, Lopez Fernandez E, Lopez JI, Angulo JC. Advances in Urological Cancer in 2022, from Basic Approaches to Clinical Management. Cancers. 2023; 15(5). DOI:10.3390/cancers15051422.

Saratxaga CLL, Asumendi A, Gardeazabal J, Izu RMM, Sanchez A, Cancho Galan G, et al. Melanoma and Nevi Subtype Histopathological Characterization with Optical Coherence Tomography. Life-Basel. 2023; 13(3). DOI:10.3390/life13030625.

Diaz Ramon JL, Gardeazabal J, Izu RM, Garrote E, Rasero J, Apraiz A, et al. Melanoma Clinical Decision Support System: An Artificial Intelligence-Based Tool to Diagnose and Predict Disease Outcome in Early-Stage Melanoma Patients. Cancers. 2023; 15(7). DOI:10.3390/cancers15072174.

Malaina I, Gonzalez Melero L, Martinez L, Salvador A, Sanchez Diez A, Asumendi A, et al. Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design. Int J Mol Sci. 2023; 24(10). DOI:10.3390/ijms24109024.

Laruelle A, Rocha A, Manini C, Lopez JI, Inarra E. Effects of Heterogeneity on Cancer: A Game Theory Perspective. Bull Math Biol. 2023; 85(8). DOI:10.1007/s11538-023-01178-9.

Orton MR, Hann E, Doran SJ, Shepherd STC, Ap Dafydd D, Spencer CE, et al. Interpretability of radiomics models is improved when using feature group selection strategies for predicting molecular and clinical targets in clear-cell renal cell carcinoma: insights from the TRACERx Renal study. Cancer Imaging. 2023; 23(1). DOI:10.1186/s40644-023-00594-3.

Garcia Vilchez R, Anazco Guenkova AMM, Dietmann S, Lopez J, Moron Calvente V, D'Ambrosi S, et al. METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer. Mol Cancer. 2023; 22(1). DOI:10.1186/s12943-023-01809-8.

Penas C, Arroyo Berdugo Y, Apraiz A, Rasero J, Munoa Hoyos I, Andollo N, et al. Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression. Sci Rep. 2023; 13(1). DOI:10.1038/s41598-023-36684-2.

Torices L, Nunes Xavier C, Lopez JI, Pulido R. Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants. PLoS One. 2023; 18(8). DOI:10.1371/journal.pone.0289369.

Manini C, Lopez Fernandez E, Cruciano N, Comandone A, Lopez JI. Benign Mesothelial Proliferations of the Tunica Vaginalis Testis. Clin Pract. 2023; 13(5): 1130-1136. DOI:10.3390/clinpract13050101.

Manini C, Laruelle A, Rocha A, Lopez JI. Convergent insights into intratumor heterogeneity. Trends Cancer. 2023. DOI:10.1016/j.trecan.2023.08.009.

Salvi M, Manini C, López JI, Fenoglio D, Molinari F. Deep learning approach for accurate prostate cancer identification and stratification using combined immunostaining of cytokeratin, p63, and racemase. Comput Med Imaging Graph. 2023; 109: 102288-102288. DOI:10.1016/j.compmedimag.2023.102288.

Nunes Xavier CE, Emaldi M, Mingo J, Oyjord T, Maelandsmo GM, Fodstad O, et al. The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma (vol 13, 7339, 2023). Sci Rep. 2023; 13(1). DOI:10.1038/s41598-023-36328-5.

Nunes Xavier CE, Emaldi M, Mingo J, Oyjord T, Maelandsmo GM, Fodstad O, et al. The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma. Sci Rep. 2023; 13(1). DOI:10.1038/s41598-023-34087-x.

Tarin Nieto A, Solano Iturri JD, Arrieta Aguirre I, Valdivia A, Etxezarraga MC, Loizate A, et al. Fibroblast Activation Protein-alpha (FAP) Identifies Stromal Invasion in Colorectal Neoplasia. Am J Surg Pathol. 2023; 47(9): 1027-1033. DOI:10.1097/PAS.0000000000002075.

Aramburu Gonzalez A, Gardeazabal Garcia J, Acebo Marinas E. Survey on Scabicides: Prescribing Habits and Perceived Effectiveness. Actas Dermo-Sifilogr. 2023. DOI:10.1016/j.ad.2022.10.055.

Villa Gonzalez JM, Gonzalez Hermosa MR, Garcia JG, Gonzalez AA, Sopena AO, Ares MP, et al. When the cure becomes worse than the disease: A case series of children with allergic contact dermatitis from chlorhexidine. J Eur Acad Dermatol Venereol. 2023; 37(7): 936-938. DOI:10.1111/jdv.19034.

Villa Gonzalez JM, Ares MP, Ramon JLD, Garcia JG, Eckert MM, del Tanago B, et al. Strategies for improving infrared thermographic imaging with smartphone accessories in dermatology. Clin Exp Dermatol. 2023; 48(8): 935-936. DOI:10.1093/ced/llad126.

Falkenhain Lopez D, Muniesa C, Estrach MT, Morillo Andujar M, Penate Y, Acebo E, et al. Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV): Data for the First 5 Years. Actas Dermo-Sifilogr. 2023; 114(4): 291-298. DOI:10.1016/j.ad.2022.11.013.

Villa Gonzalez JM, Ares MP, Lopez Soria LM, Gonzalez Hermosa MR, Garcia JG, Elgezua OL. Extensive tinea corporis caused by Trichophyton indotineae: Report of a case in Spain. J Eur Acad Dermatol Venereol. 2023. DOI:10.1111/jdv.19404.

Falkenhain Lopez D, Muniesa C, Estrach MT, Morillo Andujar M, Penate Y, Acebo E, et al. Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV): Data for the First 5 Years. Actas Dermo-Sifilogr. 2023; 114(4): 291-298. DOI:10.1016/j.ad.2022.11.010.

Placer C, Castillo J, Loizate A, Baixauli J, Echeveste A, Cristobal L, et al. The Efficacy of Porcine Dermal Collagen to Treat Complex Anal Fistulae. Results of a Multicenter Cohort. Journal Of Coloproctology (rio De Janeiro). 2023; 43(2): 68-74. DOI:10.1055/s-0043-1769485.

Aramburu Gonzalez A, Udondo Gonzalez Del Tanago B, Orbea Sopena A, Gonzalez Hermosa MR. [Translated article] Ulerythema Ophryogenes Induced by Dabrafenib. Actas Dermo-Sifilogr. 2023; 114(9): 831-832. DOI:10.1016/j.ad.2022.03.039.

Aramburu Gonzalez A, Udondo Gonzalez Del Tanago B, Orbea Sopena A, Gonzalez Hermosa MR. Ulerythema Ophryogenes Induced by Dabrafenib. Actas Dermo-Sifilogr. 2023; 114(9): 831-832. DOI:10.1016/j.ad.2022.03.019.

Jimenez Gomez N, Gonzalez Cantero A, Ruiz Villaverde R, Llamas Velasco M, de la Cueva Dobao P, Rivera Diaz R, et al. [[Translated article]]Family Planning Concerns Among Women With Psoriasis: A Descriptive, Cross-Sectional, Multicenter Study. Actas Dermo-Sifilogr. 2023. DOI:10.1016/j.ad.2023.10.030.

Jimenez Gomez N, Gonzalez Cantero A, Ruiz Villaverde R, Llamas Velasco M, de la Cueva Dobao P, Rivera Diaz R, et al. Family Planning Concerns Among Women With Psoriasis: A Descriptive, Cross-Sectional, Multicenter Study. Actas Dermo-Sifilogr. 2023. DOI:10.1016/j.ad.2023.06.015.

Navarro Matilla B, Ortiz Romero PL, Pujol Vallverdu RM, Combalia Escudero A, Zapata Paz I, Gonzalez Barca E, et al. Cost of Treating Cutaneous T-Cell Lymphoma in Spain: Analysis of MICADOS Study Data by Disease Stage. Actas Dermo-Sifilogr. 2023. DOI:10.1016/j.ad.2023.08.007.

Sanchez Diaz M, Florez A, Ara Martin M, Arias Santiago S, Botella Estrada R, Canueto J, et al. Requirements for Accessing New Dermatology Drugs in Spain: Results of the EQUIDAD Study. Actas Dermo-Sifilogr. 2023. DOI:10.1016/j.ad.2023.10.016.

Villa Gonzalez JM, Gonzalez Hermosa MR, Atxutegi Ayestaran X, Raton Nieto JA, Garcia JG, Elgezua OL. Rapid response of erythrodermic pityriasis rubra pilaris to tildrakizumab. Clin Exp Dermatol. 2023. DOI:10.1093/ced/llad352.

Mihaela F, Zoran G, Kiril T, Jeffrey S, Ming Z, Reza A, et al. Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases. Mod Pathol. 2022; 35(3): 344-351. DOI:10.1038/s41379-021-00923-6.

Wang G, Amin MB, Grossmann P, Ptakova N, Hayes M, Hartmann A, et al. Renal cell tumor with sex-cord/gonadoblastoma-like features: analysis of 6 cases. Virchows Arch. 2022; 480(2): 349-358. DOI:10.1007/s00428-021-03235-x.

Fu X, Zhao Y, Lopez JI, Rowan A, Au L, Fendler A, et al. Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study. Nat Ecol Evol. 2022; 6(1). DOI:10.1038/s41559-021-01586-x.

Alana L, Nunes Xavier CE, Zaldumbide L, Martin Guerrero I, Mosteiro L, Alba Pavon P, et al. Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma. Cancers (Basel). 2022; 14(2). DOI:10.3390/cancers14020421.

Lopez Fernandez E, Angulo JC, Lopez JI, Manini C. Urological Cancer Panorama in the Second Year of the COVID-19 Pandemic. Cancers (Basel). 2022; 14(3). DOI:10.3390/cancers14030493.

Zabala Letona A, Arruabarrena Aristorena A, Fernandez Ruiz S, Viera C, Carlevaris O, Ercilla A, et al. PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer. Oncogenesis. 2022; 11(1). DOI:10.1038/s41389-022-00382-x.

Perez Valle A, Ochoa B, Shah KN, Barreda Gomez G, Astigarraga E, Boyano MD, et al. Upregulated phospholipase D2 expression and activity is related to the metastatic properties of melanoma. Oncol Lett. 2022; 23(5). DOI:10.3892/ol.2022.13260.

Manini C, Lopez Fernandez E, Lawrie CH, Laruelle A, Angulo JC, Lopez JI. Clear Cell Renal Cell Carcinomas with Aggressive Behavior Display Low Intratumor Heterogeneity at the Histological Level. Curr Urol Rep. 2022; 23(6): 93-97. DOI:10.1007/s11934-022-01095-9.

Exposito Rodriguez A, Corta Gomez I, Dominguez Ayala M, Garcia Carrillo M, Gonzalez Garcia AI, Gutierrez Rodriguez MT, et al. Sentinel lymph node biopsy in papillary thyroid cancer: Accuracy and application in clinical practice. Cir Esp (Engl Ed). 2022; 100(7): 416-421. DOI:10.1016/j.cireng.2022.04.022.

Emaldi M, Nunes Xavier CE. B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells. Cells. 2022; 11(9). DOI:10.3390/cells11091448.

Lopez RC, Diez EA, Martitegui XM, Malcorra AB, Oleaga LI, Arzuaga Mendez J, et al. Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review. Clin Case Rep. 2022; 10(5). DOI:10.1002/ccr3.5742.

Nunes Xavier CE, Mingo J, Emaldi M, Flem Karlsen K, Maelandsmo GM, Fodstad O, et al. Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer. Front Oncol. 2022; 12. DOI:10.3389/fonc.2022.873516.

Udondo Gonzalez Del Tanago B, Aguirre Menica M, Zaldumbide Duenas L, Martinez Exposito O, Gonzalez Hermosa MR. Hundreds of vasculoproliferative skin lesions in a paediatric renal transplant recipient. Clin Exp Dermatol. 2022; 47(9): 1748-1751. DOI:10.1111/ced.15234.

Gainza Apraiz I, Julia Manresa M, Izu Belloso RM. Waxy Palms and Soles in an Adolescent Girl. Actas Dermo-Sifilogr. 2022; 113(10): 957-958. DOI:10.1016/j.ad.2021.02.032.

Navarro MB, Ortiz RPL, Pujol VRM, Combalia EA, I, Gonzalez BE, et al. COST OF ILLNESS BY DISEASE STAGE OF PATIENTS WITH MYCOSIS FUNGOIDES AND SEZARY SYNDROME: A REAL-WORLD ANALYSIS IN SPANISH PATIENTS (MICADOS STUDY). Value Health. 2022; 25(1): 69-69

Sopena AO, Gonzalez AA, Ares MP, Gardeazabal Garcia J. Polymorphous light eruption treated with omalizumab. Photodermatol Photoimmunol Photomed. 2022; 39(1): 85-86. DOI:10.1111/phpp.12814.

Manini C, Lopez JI. Updating Clear Cell Renal Cell Carcinoma (a Tribute to Prof. Ondrej Hes). Cancers (Basel). 2022; 14(16). DOI:10.3390/cancers14163990.

Abrisqueta M, Cerdido S, Sanchez Beltran J, Martinez Vicente I, Herraiz C, Lambertos A, et al. MGRN1 as a Phenotypic Determinant of Human Melanoma Cells and a Potential Biomarker. Life-Basel. 2022; 12(8). DOI:10.3390/life12081118.

Manini C, Lopez Fernandez E, I. Towards Personalized Sampling in Clear Cell Renal Cell Carcinomas. Cancers (Basel). 2022; 14(14). DOI:10.3390/cancers14143381.

Mohanty S, Lobo A, Parwani A, Adhya A, Sangoi A, Kulkarni B, et al. The Current State of Emerging Renal Oncocytic Neoplasms: A Survey of Urologic Pathologists. Lab Invest. 2022; 102(SUPPL 1): 638-639

Mohanty S, Paner G, Lobo A, Parwani A, Sangoi A, Delahunt B, et al. Uropathologists' Perspectives on Utilization of Key Morphologic and Molecular Parameters in Urothelial, Renal, and Prostatic Cancers Based on Clinical Practice Guidelines. Lab Invest. 2022; 102(SUPPL 1): 639-640

Mohanty S, Lobo A, Parwani A, Adhya A, Sangoi A, Kulkarni B, et al. The Current State of Emerging Renal Oncocytic Neoplasms: A Survey of Urologic Pathologists. Mod Pathol. 2022; 35(SUPPL 2): 638-639

Mohanty S, Paner G, Lobo A, Parwani A, Sangoi A, Delahunt B, et al. Uropathologists' Perspectives on Utilization of Key Morphologic and Molecular Parameters in Urothelial, Renal, and Prostatic Cancers Based on Clinical Practice Guidelines. Mod Pathol. 2022; 35(SUPPL 2): 639-640

Alvarez MAD, Zaffalon D, Portillo I, Bujanda L, Ibanez Sanz G, De Tejada AH, et al. IMPACT OF FIT-BASED CRC POPULATION SCREENING PROGRAM ON THE MANAGEMENT OF PT1 COLORECTAL CANCER. Gastrointest Endosc. 2022; 95(6): 165-166

van Wifferen F, Greuter MJE, Lissenberg Witte BI, Carvalho B, Meijer GA, Dekker E, et al. Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening. Prev Med. 2022: 107187-107187. DOI:10.1016/j.ypmed.2022.107187.

Muniesa C, Gallardo F, García Doval I, Estrach MT, Combalia A, Morillo Andújar M, et al. Brentuximab vedotin in the treatment of cutaneous T-cell lymphomas: Data from the Spanish Primary Cutaneous Lymphoma Registry. J Eur Acad Dermatol Venereol. 2023; 37(1): 57-64. DOI:10.1111/jdv.18563.

Gainza Apraiz I, Julia Manresa M, Izu Belloso RM. [[Translated article]]Waxy Palms and Soles in an Adolescent Girl. Actas Dermo-Sifilogr. 2022; 113(10): 957-958. DOI:10.1016/j.ad.2022.09.006.

Manini C, Imaz I, de Larrinoa AF, Lopez JI. Algorithm-Based Approach to the Histological Routine Diagnosis of Renal Oncocytic Tumors in Core Biopsy Specimens. Curr Urol Rep. 2022; 23(11): 327-333. DOI:10.1007/s11934-022-01114-9.

Manini C, Lopez JI. Ecology and games in cancer: new insights into the disease. Pathologica. 2022; 114(5): 347-351. DOI:10.32074/1591-951X-798.

Alvarez Ossorio JL, Rodrigo Aliaga M, Rodriguez Antolin A, Unda Urzaiz M, Calleja MA, de la Cruz Ruiz M, et al. Hormone sensitive protocol for metastatic prostate cancer, an update. Actas Urol Esp (Engl Ed). 2022. DOI:10.1016/j.acuroe.2022.10.002.

Loizaga Iriarte A, Lacasa Viscasillas I, Rey Gonzalez S, Santos Martin A, Gonzalo Aparicio D, Ugalde Olano A, et al. Identifying prognostic parameters related to surgical technique in patients treated by robotic radical prostatectomy. Actas Urol Esp (Engl Ed). 2022. DOI:10.1016/j.acuroe.2022.07.001.

Alcaraz Asensio A, Alvarez Ossorio JL, Cozar Olmo JM, Chantada Abal V, Juarez Soto A, Espinos EL, et al. Non-metastatic castration-resistant prostate cancer: management recommendations. Actas Urol Esp. 2022; 46(4): 193-213. DOI:10.1016/j.acuro.2021.11.004.

Alaghehbandan R, Agaimy A, Ali L, Alvarado Cabrero I, Amin MB, Boudova L, et al. A tribute to Prof. Ondrej Hes, MD, PhD (1968-2022). Mod Pathol. 2022. DOI:10.1038/s41379-022-01159-8.

Pulido R, Nunes Xavier CE. Hopes on immunotherapy targeting B7-H3 in neuroblastoma. Transl Oncol. 2023; 27: 101580-101580. DOI:10.1016/j.tranon.2022.101580.

Nunes Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Tasken KA, Malandsmo GM, et al. Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer. Pathol Res Pract. 2023; 241: 154243-154243. DOI:10.1016/j.prp.2022.154243.

Pulido R, Nunes Xavier CE. Editorial: Cell and Developmental Signalling in Neuroblastoma. Front Cell Dev Biol. 2023; 10: 1126352-1126352. DOI:10.3389/fcell.2022.1126352.

Torices L, Mingo J, Rodriguez Escudero I, Fernandez Acero T, Luna S, Nunes Xavier CE, et al. Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease. Eur J Hum Genet. 2022. DOI:10.1038/s41431-022-01265-w.

Sevilla A, Sanchez Diez A, Cobo S, Izagirre N, Martinez Cadenas C, Marti RM, et al. Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis. Life-Basel. 2022; 12(12). DOI:10.3390/life12122004.

Angulo JC, Alvarez Ossorio JL, Dominguez JL, Moyano JL, Sousa A, Fernandez JM, et al. Hyperthermic Mitomycin C in Intermediate-risk Non-muscle-invasive Bladder Cancer: Results of the HIVEC-1 Trial. Eur Urol Oncol. 2022; 6(1): 58-66. DOI:10.1016/j.euo.2022.10.008.

Gonzalez Cao M, Puertolas T, Martinez Vila C, Carrera C, Maldonado Seral C, Rodriguez Jimenez P, et al. SARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry. Clin Transl Oncol. 2023; 25(3): 768-775. DOI:10.1007/s12094-022-02985-7.

Hendriks WJJ, van Cruchten RTP, Pulido R. Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?. Front Cell Dev Biol. 2022; 10: 1051311-1051311. DOI:10.3389/fcell.2022.1051311.

Loizaga Iriarte A, Senarriaga Ruiz de la Illa N, Martin Bazaco J, Rabade Ferreiro A, Zubiaur Libano C, Unda Urzaiz M. [Background historical views of systemic treatment for muscle invasive bladder cancer.]. Arch Esp Urol. 2021; 73(10)

Manini C, Lopez JI. Insights into Urological Cancer. Cancers (Basel). 2021; 13(2). DOI:10.3390/cancers13020204.

Unanue Arza S, Arana Arri E, Portillo I, Arostegui I. [Involvement of the Primary Healthcare professionals in the Colorectal Cancer Screening Programme of the Basque Country.]. Rev Esp Salud Publica. 2021; 95

Paja M, Zafon C, Iglesias C, Ugalde A, Cameselle Teijeiro JM, Rodriguez Carnero G et al. Rate of non-invasive follicular thyroid neoplasms with papillary-like nuclear features depends on pathologist's criteria: a multicentre retrospective Southern European study with prolonged follow-up. Endocrine. 2021; 73(1): 131-140. DOI:10.1007/s12020-021-02610-7.

Barrenengoa Cuadra MJ, Munoa Manieux M, Fernandez Luco M, Angon Puras LA, Romon Gomez AJ, Azkuenaga M et al. Effectiveness of a structured group intervention based on pain neuroscience education for patients with fibromyalgia in primary care: a multicenter randomized open-label controlled trial. Eur J Pain. 2021; 25(5): 1137-1149. DOI:10.1002/ejp.1738.

Trpkov K, Williamson SR, Gill AJ, Adeniran AJ, Agaimy A, Alaghehbandan R et al. Novel, emerging and provisional renal entities: The Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol. 2021; 34(6): 1167-1184. DOI:10.1038/s41379-021-00737-6.

Torices L, de las Heras J, Arango Lasprilla JC, Cortes JM, Nunes Xavier CE, Pulido R. MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution. Molec Genet Metab Rep. 2021; 26: 100710-100710. DOI:10.1016/j.ymgmr.2021.100710.

Nagore E, Martinez Garcia MA, Gomez Olivas JD, Manrique Silva E, Martorell A, Banuls J et al. Relationship between type 2 diabetes mellitus and markers of cutaneous melanoma aggressiveness: An observational multi-centric study in 443 patients with melanoma. Br J Dermatol. 2021. DOI:10.1111/bjd.19813.

Urizar Arenaza I, Benedicto A, Perez Valle A, Osinalde N, Akimov V, Munoa Hoyos I et al. The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma. Sci Rep. 2021; 11(1): 3583-3583. DOI:10.1038/s41598-021-83169-1.

Larrinaga G, Solano Iturri JD, Errarte P, Unda M, Loizaga Iriarte A, Perez Fernandez A et al. Soluble PD-L1 Is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma. Cancers (Basel). 2021; 13(4). DOI:10.3390/cancers13040667.

Solano Iturri JD, Echevarria E, Unda M, Loizaga Iriarte A, Perez Fernandez A, Angulo JC et al. Clinical Implications of (Pro)renin Receptor (PRR) Expression in Renal Tumours. Diagnostics (Basel). 2021; 11(2). DOI:10.3390/diagnostics11020272.

Gonzalez Cao M, Carrera C, Rodriguez Moreno JF, Rodriguez Jimenez P, Antonanzas Basa M, Feltes Ochoa R et al. COVID-19 in Melanoma Patients: Results of the Spanish Melanoma Group Registry, GRAVID study. J Am Acad Dermatol. 2021; 84(5): 1412-1415. DOI:10.1016/j.jaad.2021.02.013.

Luna S, Torices L, Mingo J, Amo L, Rodriguez Escudero I, Ruiz Ibarlucea P et al. A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons. Hum Mutat. 2021; 42(5): 551-566. DOI:10.1002/humu.24186.

Trpkov K, Hes O, Williamson SR, Adeniran AJ, Agaimy A, Alaghehbandan R et al. New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol. 2021; 34(7): 1392-1424. DOI:10.1038/s41379-021-00779-w.

Manini C, Angulo JC, Lopez JI. Mimickers of Urothelial Carcinoma and the Approach to Differential Diagnosis. Clin Pract. 2021; 11(1): 110-123. DOI:10.3390/clinpract11010017.

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Ferrer SF, Valenti C, Cancho G, Ortega L, Romero C, Vazquez M, et al. Stathmin-1 expression as a complement to p16 helps identify high-grade cervical intraepithelial neoplasia with increased specificity. Virchows Arch. 2018; 473: 262-262

Li Q, Qiu B, Liang W, Wang J, Hu W, Xu S, et al. Risk Factors of Local Recurrence in EGFR-Mutant Stage III-pN2 Adenocarcinoma After Complete Resection: A Multi-Center Real-World Cohort Study. J Thorac Oncol. 2018; 13(10): 617-618. DOI:10.1016/j.jtho.2018.08.949.

Lomana E, Munoz AM, Boyano L, Sanz B, Asumendi A, Errarte P, et al. Immunohistochemical expression of Annexin A5 in renal cell carcinomas. Virchows Arch. 2018; 473: 192-192

Lomana E, Munoz AM, Boyano L, Penas C, Sanz B, de Lezcano ID, et al. Prognostic impact of Pirin expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 192-192

Andres L, Velasco V, Saiz M, Mosteiro L, Caamano V, Malaxetxebarria S, et al. Primary diffuse large B-cell lymphoma of the breast: report of 8 cases. Virchows Arch. 2018; 473: 200-200

Munoz AM, Lomana EF, Penas C, Sanz B, Perez I, Asumendi A, et al. Prognostic impact of RKIP expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 337-337

Lomana E, Munoz AM, Boyano L, Sanz B, Asumendi A, Errarte P, et al. Immunohistochemical expression of Annexin A5 in renal cell carcinomas. Virchows Arch. 2018; 473: 192-192

Andres L, Velasco V, Saiz M, Mosteiro L, Caamano V, Malaxetxebarria S, et al. Mullerian adenosarcoma of the female genital tract: report of 8 cases and review of the literature. Virchows Arch. 2018; 473: 263-263

Williamson SR, Rao P, Hes O, Epstein J, Picken M, Zhou M, et al. Challenges in Pathologic Staging of Renal Cell Carcinoma: An Interobserver Variability Study of Urologic Pathologists. Lab Invest. 2018; 98: 399-399

Lomana E, Munoz AM, Boyano L, Penas C, Sanz B, de Lezcano ID, et al. Prognostic impact of Pirin expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 192-192

Saiz M, Caamano V, Zaldumbide L, Idiondo E, Munoz AM, Mosteiro L, et al. Negative Association Between PD1/PD-L1 Inhibitor Expression and ROS1, ALK and EGFR Mutations in Non-Small Cell Lung Cancer. Lab Invest. 2018; 98: 749-749

Munoz AM, Lomana EF, Penas C, Sanz B, Perez I, Asumendi A, et al. Prognostic impact of RKIP expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 337-337

Zaldumbide L, Aurtenetxe O, Erramuzpe A, Saiz M, Lopez Almaraz R, Caamano V, et al. Neuroblastoma PTPome Analysis Unveils Association of PTPN1 And DUSP5 Expression With Poor Prognosis. Lab Invest. 2018; 98(1): 720-720

Saiz M, Caamano V, Zaldumbide L, Idiondo E, Munoz AM, Mosteiro L, et al. Negative Association Between PD1/PD-L1 Inhibitor Expression and ROS1, ALK and EGFR Mutations in Non-Small Cell Lung Cancer. Lab Invest. 2018; 98: 749-749

Unda Urzáiz M, Alonso Herreros JM, Fernández Gómez JM, Gaspar Carreño M, Cozar Olmos JM, Cercós Lleti AC. Revisión de la evidencia sobre el manejo de medicamentos y productos peligrosos en los servicios de Urología; documento de consenso entre la Asociación Española de Urología y la Sociedad Española de Farmacia Hospitalaria. Farm Hosp. 2018; 42(5): 212-215. DOI:10.7399/fh.11014.

Zarrazquin Arizaga I, Fernandez Atucha A, Kortajarena M, Torres Unda J, Irazusta A, Ruiz Litago F, et al. Associations of Anthropometric Characteristics, Dietary Habits, and Aerobic Capacity With Cardiovascular Risk Factors of Health-Science Students. Biol Res Nurs. 2018; 20(5): 549-557. DOI:10.1177/1099800418788652.

Cabello I, Alia P, Pintó X, Muniesa C, Fernandez Misa R, Peñate Y, et al. Association of APOA5 and APOC3 Genetic Polymorphisms with Severity of Hypertriglyceridemia in Patients with Cutaneous T-Cell Lymphoma Treated with Bexarotene. JAMA Dermatol. 2018; 154(12): 1424-1431. DOI:10.1001/jamadermatol.2018.3679.

Gomez Ezeiza J, Torres Unda J, Tam N, Irazusta J, Granados C, Santos Concejero J. Race walking gait and its influence on race walking economy in world-class race walkers. J Sports Sci. 2018; 36(19): 2235-2241. DOI:10.1080/02640414.2018.1449086.

Ortiz Romero PL, Servitje O, Estrach MT, Izu Belloso RM, Fernandez Misa R, Gallardo F, et al. Cost of early-stage mycosis fungoides treatments in Spain. Eur J Cancer. 2018; 101: 30-30. DOI:10.1016/j.ejca.2018.07.286.

Hervas G, Ruiz Litago F, Irazusta J, Fernandez Atutxa A, Belen Fraile Bermudez A, Zarrazquin I. Physical Activity, Physical Fitness, Body Composition, and Nutrition Are Associated with Bone Status in University Students. Nutrients. 2018; 10(1). DOI:10.3390/nu10010061.

Gianzo M, Urizar Arenaza I, Munoa Hoyos I, Larreategui Z, Irazusta J, Subiran N. Human Sperm Aminopeptidase N is related to embryo development and viability during ART. Hum Reprod. 2018; 33(1): 164-164

Lascurain Aguirrebena I, Newham D, Irazusta J, Seco J, Critchley DJ. Reliability of a Method to Measure Neck Surface Electromyography, Kinematics, and Pain Occurrence in Participants With Neck Pain. J MANIP PHYSIOL THER. 2018; 41(5): 413-424. DOI:10.1016/j.jmpt.2017.10.013.

Etxegarai U, Portillo E, Irazusta J, Arriandiaga A, Cabanes I. Estimation of lactate threshold with machine learning techniques in recreational runners. Appl Soft Comput. 2018; 63: 181-196. DOI:10.1016/j.asoc.2017.11.036.

Nunes Xavier CE, Mingo J, Pulido R, Lopez JI. Androgen-responsive PTPN1 immunostaining is associated to biochemical recurrence in prostate cancer. Virchows Arch. 2018; 473(1): 187-188

Pérez Ferriols A, Barnadas M, Gardeazábal J, de Argila D, Carrascosa JM, Aguilera P, et al. Solar Urticaria: Epidemiology and Clinical Phenotypes in a Spanish Series of 224 Patients. Actas Dermosifiliogr. 2017; 108(2): 132-139. DOI:10.1016/j.ad.2016.09.003.

De la Fuente IM, Malaina I, Perez Samartin A, Dolores Boyano M, Perez Yarza G, Bringas C, et al. Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes. Sci Rep. 2017; 7: 41791-41791. DOI:10.1038/srep41791.

Gomez Iturriaga A, Casquero F, Lopez JI, Urresola A, Ezquerro A, Buscher D, et al. Transperineal biopsies of MRI-detected aggressive index lesions in low- and intermediate-risk prostate cancer patients: Implications for treatment decision. Brachytherapy. 2017; 16(1): 201-206. DOI:10.1016/j.brachy.2016.11.004.

López JI, Cortés JM. Multisite tumor sampling: a new tumor selection method to enhance intratumor heterogeneity detection. Hum Pathol. 2017; 64: 1-6. DOI:10.1016/j.humpath.2017.02.010.

Oliver MD, Fernández Acero T, Luna S, Rodríguez Escudero I, Molina M, Pulido R, et al. Insights into the pathological mechanisms of p85 alpha mutations using a yeast-based phosphatidylinositol 3-kinase model. Biosci Rep. 2017; 37(2). DOI:10.1042/BSR20160258.

López JI, Erramuzpe A, Guarch R, Cortés JM, Pulido R, Llarena R, et al. CD34 immunostaining enhances a distinct pattern of intratumor angiogenesis with prognostic implications in clear cell renal cell carcinoma. APMIS. 2017; 125(2): 128-133. DOI:10.1111/apm.12649.

Panfoli I, Ponassi M, Ravera S, Calzia D, Beitia M, Morelli A, et al. Tracking protons from respiratory chain complexes to ATP synthase c-subunit: The critical role of serine and threonine residues. Biochem Biophys Res Commun. 2017; 482(4): 922-927. DOI:10.1016/j.bbrc.2016.11.134.

Loizaga Iriarte A, Rodriguez Antolin A, Miñana B, Lacasa Viscasillas I, Senarriaga Ruiz de la Illa N, Cozar Olmo JM, et al. Castrate resistant prostate cancer. Consensus recommendations of the Spanish Association of Urology. Actas Urol Esp. 2017; 41(3): 141-145. DOI:10.1016/j.acuro.2016.09.001.

Fraile Bermúdez AB, Kortajarena M, Zarrazquin I, Irazusta A, Fernandez Atutxa A, Ruiz Litago F, et al. Physical activity and dietary habits related to cardiovascular risk in independent community-living older women. Exp Gerontol. 2017; 92: 46-51. DOI:10.1016/j.exger.2017.03.012.

Errarte P, Beitia M, Perez I, Manterola L, Lawrie CH, Solano Iturri JD, et al. Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients. PLoS One. 2017; 12(8). DOI:10.1371/journal.pone.0181711.

Luna S, Mingo J, Amo L, Rodriguez Escudero I, Erramuzpe A, Molina M, et al. Readthrough response of pathogenic premature termination codons at PTEN gene: implications in precision therapy for PHTS patients. Ann Oncol. 2017; 28(7)

Mingo J, Luna S, Gaafar A, Ruiz R, Carracedo A, Guerra I, et al. The relevance of precision epitope mapping for accurate oncologic diagnostic based on PTEN protein expression in tumours. Ann Oncol. 2017; 28(7)

Pulido R, Nunes Xavier C, Aurtenetxe O, Zaldumbide L, Erramuzpe A, Lopez R, et al. Neuroblastoma PTPome analysis unveils association of DUSP5 and PTPN1 expression with poor prognosis. Ann Oncol. 2017; 28(7)

Garcia Ariza M, Echebarria Barona A, Lopez Almaraz R, Adan Pedroso R, Bilbao Salcines N, Ricondo De Diego A, et al. Tumors of the Central Nervous System in the First Year of Life. One Single Institution Experience. Pediatr Blood Cancer. 2017; 64(3): 462-462

Garcia Ariza M, Lopez Almaraz R, Echebarria Barona A, Adan Pedroso R, Ojinaga Nino I, Ricondo De Diego A, et al. Experience of the Management of Central Nervous System Tumors in Children Younger than 5 Years-Old in the Last 15 Years. Pediatr Blood Cancer. 2017; 64(3): 304-304

Alcaraz A, Martínez Piñeiro L, Rodríguez A, Rubio J, Borque Á, Burgos J, et al. Consensus on castration-resistant prostate cancer management in Spain. Arch Esp Urol. 2017; 70(9): 777-791

Trpkov K, Abou Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC) Further Morphologic and Molecular Characterization of ESC RCC as a Distinct Entity. Am J Surg Pathol. 2017; 41(10): 1299-1308. DOI:10.1097/PAS.0000000000000838.

Lopez JI, Angulo JC, Martin A, Sanchez Chapado M, Gonzalez Corpas A, Colas B, et al. A DNA hypermethylation profile reveals new potential biomarkers for the evaluation of prognosis in urothelial bladder cancer. APMIS. 2017; 125(9): 787-796. DOI:10.1111/apm.12719.

De Petris G, De Marco L, Lopez JI. Drug-induced gastrointestinal injury (DIGI). Updates, reflections and key points. Pathologica. 2017; 109(2): 97-109

Lopez JI, De Petris G. Discovering intratumor heterogeneity: the next frontier for pathologists. Pathologica. 2017; 109(2): 110-113

Cortes JM, de Petris G, Lopez JI. Detection of intratumor Heterogeneity in Modern Pathology: A Multisite tumor sampling Perspective. Front Med (Lausanne). 2017; 4: 25-25. DOI:10.3389/fmed.2017.00025.

Trpkov K, Athanazio D, Magi Galluzzi C, Yilmaz H, Clouston D, Agaimy A, et al. Biphasic Papillary Renal Cell Carcinoma Is a Rare and Distinct Morphologic Variant Clinicopathologic Study of 24 Novel Cases. Mod Pathol. 2017; 30(2): 264-264

Villaverde VC, Vadillo MG, Gonzalez LM, Camin MS, Benito VV, Alvarez LA, et al. Pancreatic mx diagnosis of Clear Renal Cell Carcinoma (CRCC) by fnab-eus-guided: Review of 2 cases. Virchows Arch. 2017; 471(1): 310-310

Cazeau C, Blei F, Hermosa MDFG, Cavalli R, Boccara O, Folster Holst R, et al. Burden of Infantile Hemangioma on Family: An International Observational Cross-Sectional Study. Pediatr Dermatol. 2017; 34(3): 295-302. DOI:10.1111/pde.13133.

Trpkov K, Athanazio D, Magi Galluzzi C, Yilmaz H, Clouston D, Agaimy A, et al. Biphasic Papillary Renal Cell Carcinoma Is a Rare and Distinct Morphologic Variant - Clinicopathologic Study of 24 Novel Cases. Lab Invest. 2017; 97(1): 266-266

Torres Unda J, Polo V, Dunabeitia I, Bidaurrazaga Letona I, Garcia Gil M, Rodriguez Larrad A, et al. The Feldenkrais Method improves functioning and body balance in people with intellectual disability in supported employment: A randomized clinical trial. Res Dev Disabil. 2017; 70: 104-112. DOI:10.1016/j.ridd.2017.08.012.

Tamayo Orbegozo E, Amo L, Riñón M, Nieto N, Amutio E, Maruri N, et al. Podocalyxin promotes proliferation and survival in mature B-cell non-Hodgkin lymphoma cells. Oncotarget. 2017; 8(59): 99722-99739. DOI:10.18632/oncotarget.21283.

Miles J, Applebee CJ, Leboucher P, Lopez Fernandez S, Lee DJ, Guarch R, et al. Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma. BBA Clin. 2017; 8: 97-102. DOI:10.1016/j.bbacli.2017.10.002.

Wong KK, Hussain FA, Loo SK, Lopez JI. Cancer/testis antigen SPATA19 is frequently expressed in benign prostatic hyperplasia and prostate cancer. APMIS. 2017; 125(12): 1092-1101. DOI:10.1111/apm.12775.

Urizar Arenaza I, Osinalde N, Gianzo M, Matorras R, Exposito A, Irazusta J, et al. Label-free phosphoproteomics reveals a novel calcium signaling pathway activated via kappa-opioid receptor in human spermatozoa. Hum Reprod. 2017; 32(1): 58-59

Gianzo M, Larreategui Z, Munoa Hoyos I, Urizar Arenaza I, Irazusta J, Subiran N. The (Pro)renin receptor is expressed in human sperm cells and is related to sperm quality and embryo development. Hum Reprod. 2017; 32(1): 154-155

Zabala Letona A, Arruabarrena Aristorena A, Martín N, Fernandez Ruiz S, Sutherland JD, Clasquin M, et al. mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. Nature. 2017; 547(7661): 109-109. DOI:10.1038/nature22964.

Villaverde VC, Vadillo MG, Gonzalez LM, Benito VV, Camin MS, Alvarez LA, et al. Chondromyxoid fibroma: Report of three cases. Virchows Arch. 2017; 471(1): 260-261

Camin MS, Gonzalez LM, Benito VV, Unibaso SM, Villaverde VC, Vadillo MG, et al. Tumours of the thymus: Review of cases in Cruces Universitary Hospital over the last 5 years. Virchows Arch. 2017; 471(1): 346-346

Camin MS, Gonzalez LM, Benito VV, Unibaso SM, Villaverde VC, Vadillo MG, et al. Extramedullary hematopoiesis in adults: Review of cases in Cruces Universitary Hospital over the last 20 years. Virchows Arch. 2017; 471(1): 143-143

Gómez Veiga F, Rodríguez Antolín A, Miñana B, Hernández C, Suárez JF, Fernández Gómez JM, et al. Diagnosis and treatment for clinically localized prostate cancer. Adherence to the European Association of Urology clinical guidelines in a nationwide population-based study - GESCAP group. Actas Urol Esp. 2017; 41(6): 359-367. DOI:10.1016/j.acuro.2016.10.009.

Lago CP, Quiroga Alvarez A, Arroyo Berdugo Y, Peerez Valle A, Aguuera Lorente A, Asumendi Mallea A, et al. Raf kinase inhibitor protein down regulation does not modify malignant properties of V600E BRAF mutated melanoma cells. J Invest Dermatol. 2017; 137(10): 286-286

Belloso RI. Mycosis Fungoides in Pediatric Patients: A Diagnostic Challenge. Actas Dermosifiliogr. 2017; 108(6): 499-499. DOI:10.1016/j.ad.2017.01.008.

Royo F, Zuñiga Garcia P, Torrano V, Loizaga A, Sanchez Mosquera P, Ugalde Olano A, et al. Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer. Oncotarget. 2016; 7(6): 6835-6846. DOI:10.18632/oncotarget.6899.

Maroto P, Solsona E, Gallardo E, Mellado B, Morote J, Arranz JT, et al. Expert opinion on first-line therapy in the treatment of castration-resistant prostate cancer. Crit Rev Oncol Hematol. 2016; 100: 127-136. DOI:10.1016/j.critrevonc.2015.07.011.

Palou Redorta J, Solsona E, Angulo J, Fernández JM, Madero R, Unda M, et al. Retrospective study of various conservative treatment options with bacille Calmette-Guerin in bladder urothelial carcinoma T1G3: Maintenance therapy. Actas Urol Esp. 2016; 40(6): 370-377. DOI:10.1016/j.acuro.2015.12.009.

Torrano V, Valcarcel Jimenez L, Cortazar AR, Liu X, Urosevic J, Castillo Martin M, et al. The metabolic co-regulator PGC1 alpha suppresses prostate cancer metastasis. Nat Cell Biol. 2016; 18(6): 645-645. DOI:10.1038/ncb3357.

Quintana JM, Gonzalez N, Anton Ladislao A, Redondo M, Bare M, Fernandez de Larrea N, et al. Colorectal cancer health services research study protocol: the CCR-CARESS observational prospective cohort project. BMC Cancer. 2016; 16(1): 435-435. DOI:10.1186/s12885-016-2475-y.

Lopez JI. Gleason and Fuhrman no longer make the grade. Histopathology. 2016; 69(2): 340-341. DOI:10.1111/his.12946.

Lopez JI, Errarte P, Erramuzpe A, Guarch R, Cortes JM, Angulo JC, et al. Fibroblast activation protein predicts prognosis in clear cell renal cell carcinoma. Hum Pathol. 2016; 54: 100-105. DOI:10.1016/j.humpath.2016.03.009.

Ortega Martinez I, Gardeazabal J, Erramuzpe A, Sanchez Diez A, Cortes J, Garcia Vazquez MD, et al. Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I-II early-stage melanoma. Int J Cancer. 2016; 139(7): 1598-1607. DOI:10.1002/ijc.30202.

Mingo J, Erramuzpe A, Luna S, Aurtenetxe O, Amo L, Diez I, et al. One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections. PLoS One. 2016; 11(8). DOI:10.1371/journal.pone.0160972.

Miñana B, Rodríguez Antolín A, Gómez Veiga F, Hernández C, Suárez JF, Fernández Gómez JM, et al. Treatment trends for clinically localised prostate cancer. National population analysis: GESCAP group. Actas Urol Esp. 2016; 40(4): 209-216. DOI:10.1016/j.acuro.2015.09.005.

Torrano V, Royo F, Peinado H, Loizaga Iriarte A, Unda M, Falcon Perez JM, et al. Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer. Curr Opin Pharmacol. 2016; 29: 47-53. DOI:10.1016/j.coph.2016.06.003.

Alcaraz A, Carballido Rodriguez J, Unda Urzaiz M, Medina Lopez R, Ruiz Cerda JL, Rodriguez Rubio F, et al. Quality of life in patients with lower urinary tract symptoms associated with BPH: change over time in real-life practice according to treatment-the QUALIPROST study. Int Urol Nephrol. 2016; 48(5): 645-656. DOI:10.1007/s11255-015-1206-7.

Royo F, Zuniga Garcia P, Sanchez Mosquera P, Egia A, Perez A, Loizaga A, et al. Different EV enrichment methods suitable for clinical settings yield different subpopulations of urinary extracellular vesicles from human samples. J Extracell Vesicles. 2016; 5. DOI:10.3402/jev.v5.29497.

Olaia A, laura Z, Idoia M, Ayman G, Miguel G, Aurora N. SPANISH EXPERIENCE IN PEDIATRIC MEDULLOBLASTOMA. Neuro-Oncology. 2016; 18(3): 114-115

Hes O, Condom Mundo E, Peckova K, Lopez JI, Martinek P, Vanecek T, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma A Distinctive Subtype of Papillary Renal Cell Carcinoma?. Am J Surg Pathol. 2016; 40(5): 664-675. DOI:10.1097/PAS.0000000000000639.

Gomez Iturriaga A, Casquero F, Urresola A, Ezquerro A, Lopez JI, Espinosa JM, et al. Dose escalation to dominant intraprostatic lesions with MRI-transrectal ultrasound fusion High-Dose-Rate prostate brachytherapy. Prospective phase II trial. Radiother Oncol. 2016; 119(1): 91-96. DOI:10.1016/j.radonc.2016.02.004.

Alonso A, Pulido R. The extended human PTPome: a growing tyrosine phosphatase family. FEBS J. 2016; 283(8): 1404-1429. DOI:10.1111/febs.13600.

Calmels N, Greff G, Obringer C, Kempf N, Gasnier C, Tarabeux J, et al. Uncommon nucleotide excision repair phenotypes revealed by targeted high-throughput sequencing. Orphanet J Rare Dis. 2016; 11: 26-26. DOI:10.1186/s13023-016-0408-0.

Hernando B, Ibarrola Villava M, Fernandez LP, Pena Chilet M, Llorca Cardenosa M, Oltra SS, et al. Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin. Biol Sex Differ. 2016; 7: 17-17. DOI:10.1186/s13293-016-0070-1.

Zaldumbide L, Erramuzpe A, Guarch R, Pulido R, Cortes JM, Lopez JI. Snail heterogeneity in clear cell renal cell carcinoma. BMC Cancer. 2016; 16: 194-194. DOI:10.1186/s12885-016-2237-x.

Knafo S, Sanchez Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, et al. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nat Neurosci. 2016; 19(3): 443-443. DOI:10.1038/nn.4225.

Lopez JI. Intratumor heterogeneity in clear cell renal cell carcinoma: a review for the practicing pathologist. APMIS. 2016; 124(3): 153-159. DOI:10.1111/apm.12500.

Angulo JC, Andres G, Ashour N, Sanchez Chapado M, Lopez JI, Ropero S. Development of Castration Resistant Prostate Cancer can be Predicted by a DNA Hypermethylation Profile. J Urol. 2016; 195(3): 619-626. DOI:10.1016/j.juro.2015.10.172.

Nunez O, Roman A, Johnson SR, Inoue Y, Hirose M, Casanova A, et al. Study of breast cancer incidence in patients of lymphangioleiomyomatosis. Breast Cancer Res Treat. 2016; 156(1): 195-201. DOI:10.1007/s10549-016-3737-8.

Lopez JI, Mosteiro L, Guarch R, Larrinaga G, Pulido R, Angulo JC. Low-grade metastases in high-grade clear cell renal cell carcinomas A clinicopathologic study of 4 cases with an insight into the role of mesenchymal-to-epithelial transition process. Ann Diagn Pathol. 2016; 20: 13-18. DOI:10.1016/j.anndiagpath.2015.10.011.

Angulo JC, Lopez JI, Dorado JF, Sanchez Chapado M, Colas B, Ropero S. A DNA Hypermethylation Profile Independently Predicts Biochemical Recurrence Following Radical Prostatectomy. UrolInt. 2016; 97(1): 16-25. DOI:10.1159/000446446.

Urizar Arenaza I, Estomba H, Munoa Hoyos I, Matorras R, Esposito A, Candenas L, et al. The opioid peptide beta-endorphin stimulates acrosome reaction in human spermatozoa. Andrology. 2016; 4(1): 143-151. DOI:10.1111/andr.12133.

Angulo JC, Lopez JI, Fernandez Arias M. Revealing the production process of Joaquin Albarran's Les Tumeurs de la Vessie 125 years after its writing. Actas Urol Esp. 2016; 40(7): 463-469. DOI:10.1016/j.acuro.2016.01.008.

Planelles M, Macias L, Peiro G, Bulimbasic S, Hes O, Robles A, et al. Rheb/mTOR/p70s6k Cascade and TFE3 Expression in Conventional and Sclerosing PEComas of the Urinary Tract. Appl Immunohistochem. 2016; 24(7): 514-520. DOI:10.1097/PAI.0000000000000209.

Trpkov K, Hes O, Bonert M, Lopez JI, Bonsib SM, Nesi G, et al. Eosinophilic, Solid, and Cystic Renal Cell Carcinoma Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women. Am J Surg Pathol. 2016; 40(1): 60-71. DOI:10.1097/pas.0000000000000508.

Foix MP, Dunatov A, Martinek P, Condom Mundo E, Suster S, Sperga M, et al. Multicystic Chromophobe Renal Cell Carcinoma: A Challenging Unusual Architectural Variant. Morphological, Immunohistochemical and arrayCGH Analysis of 11 Cases. Mod Pathol. 2016; 29(2): 253-254

Trpkov K, Abou Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC): A Novel Entity with Distinct Molecular Karyotype. Mod Pathol. 2016; 29(2): 267-267

Pane Foix M, Dunatov A, Martinek P, Condom Mundo E, Suster S, Sperga M, et al. Multicystic Chromophobe Renal Cell Carcinoma: A Challenging Unusual Architectural Variant. Morphological, Immunohistochemical and arrayCGH Analysis of 11 Cases. Lab Invest. 2016; 96(1): 253-254

Trpkov K, Abou Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC): A Novel Entity with Distinct Molecular Karyotype. Lab Invest. 2016; 96(1): 267-267

Angulo JC, Lopez JI, Ropero S. DNA Methylation and Urological Cancer, a Step Towards Personalized Medicine: Current and Future Prospects. Mol Diagn Ther. 2016; 20(6): 531-549. DOI:10.1007/s40291-016-0231-2.

Angulo JC, Redondo C, Sanchez Chapado M, Colas B, Ropero S, Lopez JI. Survival predictors in patients with prostate adenocarcinoma with hormonal blockade. Pathol Res Pract. 2016; 212(10): 899-903. DOI:10.1016/j.prp.2016.07.012.

Guergue Diaz de Cerio O, Barrutia Borque A, Gardeazabal Garcia J. Scombroid Poisoning: A Practical Approach. Actas Dermosifiliogr. 2016; 107(7): 567-571. DOI:10.1016/j.ad.2016.02.010.

Aguilera Arjona J, De Galvez Aranda MV, De Argila D, Perez Ferriols A, Rodriguez Granados T, Gardeazabal J, et al. STANDARDIZATION OF A NEW PHOTODIAGNOSIS METHOD BASED ON LEDS FOR PATIENTS WITH SOLAR URTICARIA. Photodermatol Photoimmunol Photomed. 2016; 32(4): 230-230

de Quintana Sancho A, Diaz Ramon JL, Acebo Marinas E, Canovas Fernandez A. Treatment of the Mucocutaneous Manifestations of Hereditary Hemorrhagic Telangiectasia Using the Nd:YAG Laser (1.064nm). Actas Dermosifiliogr. 2016; 107(2): 171-173. DOI:10.1016/j.ad.2015.06.011.

Gianzo M, Munoa Hoyos I, Urizar Arenaza I, Larreategui Z, Quintana F, Garrido N, et al. Angiotensin II type 2 receptor is expressed in human sperm cells and is involved in sperm motility. Fertil Steril. 2016; 105(3): 608-616. DOI:10.1016/j.fertnstert.2015.11.004.

Arrieta H, Torres Unda J, Maria Gil S, Irazusta J. Relative age effect and performance in the U16, U18 and U20 European Basketball Championships. J Sports Sci. 2016; 34(16): 1530-1534. DOI:10.1080/02640414.2015.1122204.

Barrutia Borque A, Acebo E, Gardeazabal Garcia J. Erythematous and Hyperpigmented Macules on the Feet. Am J Dermatopathol. 2016; 38(12): 902-902. DOI:10.1097/DAD.0000000000000399.

Pane Foix M, Dunatov A, Martinek P, Condom Mundo E, Suster S, Sperga M, et al. Morphological, immunohistochemical, and chromosomal analysis of multicystic chromophobe renal cell carcinoma, an architecturally unusual challenging variant. Virchows Arch. 2016; 469(6): 669-678. DOI:10.1007/s00428-016-2022-x.

Lopez JI, Cortes JM. A multi-site cutting device implements efficiently the divide-and-conquer strategy in tumor sampling. F1000Res. 2016; 5: 1587-1587. DOI:10.12688/f1000research.9091.2.

Luna S, Mingo J, Aurtenetxe O, Blanco L, Amo L, Schepens J, et al. Tailor-Made Protein Tyrosine Phosphatases: In Vitro Site-Directed Mutagenesis of PTEN and PTPRZ-B. Methods Mol Biol. 2016; 1447: 79-93. DOI:10.1007/978-1-4939-3746-2_5.

Lopez JI. Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma. F1000Res. 2016; 5: 607-607. DOI:10.12688/f1000research.8451.2.

Lopez JI, Cortes JM. A divide-and-conquer strategy in tumor sampling enhances detection of intratumor heterogeneity in routine pathology: A modeling approach in clear cell renal cell carcinoma. F1000Res. 2016; 5: 385-385. DOI:10.12688/f1000research.8196.2.

Errarte P, Guarch R, Pulido R, Blanco L, Nunes Xavier CE, Beitia M, et al. The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases. PLoS One. 2016; 11(12). DOI:10.1371/journal.pone.0169105.

Villaverde VC, Mosteiro L, Guarch R, Pulido R, Lopez JI. Low-grade metastases from Clear Cell Renal Cell Carcinomas (CCRCC): A study of E- and N-Cadherin expression in 19 cases. Virchows Arch. 2016; 469(1): 336-336

Gil A, López JI, Pulido R. Assessing PTEN Subcellular Localization. Methods Mol Biol. 2016; 1388: 169-186. DOI:10.1007/978-1-4939-3299-3_12.

Guergué Díaz de Cerio O, González Hermosa MD, Ballestero Díez M. Bullous Scabies in a 5-Year-Old Child. J Pediatr. 2016; 179: 270-362. DOI:10.1016/j.jpeds.2016.08.078.

Guergué Diaz de Cerio O, Rubio Lombraña M, Barrutia Borque A, González Hermosa MR. Father-to-Newborn Transmission of Herpes Simplex Virus Infection: A Sweet but Bitter Kiss. Actas Dermosifiliogr. 2016; 107(9): 797-798. DOI:10.1016/j.ad.2016.04.011.

Nunes Xavier CE, Pulido R. Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome. Methods Mol Biol. 2016; 1447: 25-37. DOI:10.1007/978-1-4939-3746-2_2.

Alonso A, Nunes Xavier CE, Bayón Y, Pulido R. The Extended Family of Protein Tyrosine Phosphatases. Methods Mol Biol. 2016; 1447: 1-23. DOI:10.1007/978-1-4939-3746-2_1.

Alonso A, Pulido R. The extended human PTPome: a growing tyrosine phosphatase family (vol 283, pg 1404, 2016). FEBS J. 2016; 283(11): 2197-2201. DOI:10.1111/febs.13748.

Hes O, Condom Mundo E, Peckova K, Lopez JI, Martinek P, Vanecek T, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma: A Distinctive Subtype of Papillary Renal Cell Carcinoma?. Am J Surg Pathol. 2016; 40(5): 664-675. DOI:10.1097/PAS.0000000000000639.

Trpkov K, Hes O, Bonert M, Lopez JI, Bonsib SM, Nesi G, et al. Eosinophilic, Solid, and Cystic Renal Cell Carcinoma: Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women. Am J Surg Pathol. 2016; 40(1): 60-71. DOI:10.1097/PAS.0000000000000508.

Royo F, Diwan I, Tackett MR, Zuñiga P, Sanchez Mosquera P, Loizaga Iriarte A, et al. Comparative miRNA Analysis of Urine Extracellular Vesicles Isolated through Five Different Methods. Cancers (Basel). 2016; 8(12). DOI:10.3390/cancers8120112.

Barrutia Borque A, Acebo E, Gardeazabal García J. Erythematous and Hyperpigmented Macules on the Feet. Am J Dermatopathol. 2016; 38(12): 902-903. DOI:10.1097/DAD.0000000000000398.

Eguizabal C, Zenarruzabeitia O, Monge J, Santos S, Vesga MA, Maruri N, et al. Natural killer cells for cancer immunotherapy: pluripotent stem cells-derived NK cells as an immunotherapeutic perspective. Front Immunol. 2015; 5: 439-439. DOI:10.3389/fimmu.2014.00439.

Solsona E, Madero R, Chantada V, Fernandez JM, Zabala JA, Portillo JA, et al. Sequential Combination of Mitomycin C Plus Bacillus Calmette-Guerin (BCG) Is More Effective but More Toxic Than BCG Alone in Patients with Non-Muscle-invasive Bladder Cancer in Intermediate-and High-risk Patients: Final Outcome of CUETO 93009, a Randomized Prospective Trial. Eur Urol. 2015; 67(3): 508-516. DOI:10.1016/j.eururo.2014.09.026.

Zaldumbide L, Erramuzpe A, Guarch R, Cortés JM, López JI. Large (> 3.8 cm) clear cell renal cell carcinomas are morphologically and immunohistochemically heterogeneous. Virchows Arch. 2015; 466(1): 61-66. DOI:10.1007/s00428-014-1673-8.

Hen O, Condom Mundo E, Lopez J, Peckova K, Martinek P, Rotterova P, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma Is Probably Part of the Spectrum of Papillary Renal Cell Carcinoma: Clinicopathologic, Immunohistochemical and Molecular Genetic Analysis of 22 Cases. Lab Invest. 2015; 95(1): 228-228

Peckova K, Ohe C, Kuroda N, Martinek P, Bulimbasic S, Montiel DP, et al. Chromophobe Renal Cell Carcinoma With Neuroendocrine Differentiation and Neuroendocrine-Like Features. Morphologic, Immunohistochemical, Ultrastructural, and ArrayCGH Analysis of 18 Cases. Lab Invest. 2015; 95(1): 250-250

Pulido R. A rapid guide to PTEN function. Methods. 2015; 77-78: 1-2. DOI:10.1016/j.ymeth.2015.02.006.

Pulido R. PTEN: A yin-yang master regulator protein in health and disease. Methods. 2015; 77-78: 3-10. DOI:10.1016/j.ymeth.2015.02.009.

Sotelo NS, Schepens JTG, Valiente M, Hendriks WJJ, Pulido R. PTEN-PDZ domain interactions: Binding of PTEN to PDZ domains of PTPN13. Methods. 2015; 77-78: 147-156. DOI:10.1016/j.ymeth.2014.10.017.

Rodriguez Escudero I, Fernandez Acero T, Bravo I, Leslie NR, Pulido R, Molina M, et al. Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo. Methods. 2015; 77-78: 172-179. DOI:10.1016/j.ymeth.2014.10.020.

Gil A, Rodriguez Escudero I, Stumpf M, Molina M, Cid VJ, Pulido R. A Functional Dissection of PTEN N-Terminus: Implications in PTEN Subcellular Targeting and Tumor Suppressor Activity. PLoS One. 2015; 10(4). DOI:10.1371/journal.pone.0119287.

Larrinaga G, Perez I, Sanz B, Beitia M, Errarte P, Fernandez A, et al. Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis. PLoS One. 2015; 10(3). DOI:10.1371/journal.pone.0119436.

Kuroda N, Karashima T, Inoue K, Kasajima A, Ohe C, Kawakami F, et al. REVIEW OF RENAL CELL CARCINOMA WITH RHABDOID FEATURES WITH FOCUS ON CLINICAL AND PATHOBIOLOGICAL ASPECTS. Pol J Pathol. 2015; 66(1): 3-8. DOI:10.5114/PJP.2015.51147.

Lopez JI, Larrinaga G, Kuroda N, Angulo JC. The normal and pathologic renal medulla: A comprehensive overview. Pathol Res Pract. 2015; 211(4): 271-280. DOI:10.1016/j.prp.2014.12.009.

Sanz B, Perez I, Beitia M, Errarte P, Fernandez A, Blanco L, et al. Aminopeptidase N Activity Predicts 5-Year Survival in Colorectal Cancer Patients. J Invest Med. 2015; 63(5): 740-746. DOI:10.1097/JIM.0000000000000199.

Perez I, Blanco L, Sanz B, Errarte P, Ariz U, Beitia M, et al. Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer. Int J Med Sci. 2015; 12(6): 458-467. DOI:10.7150/ijms.11808.

Fernandez Atucha A, Echevarria E, Larrinaga G, Gil J, Martinez Cengotitabengoa M, Gonzalez Pinto AM, et al. Plasma peptidases as prognostic biomarkers in patients with first-episode psychosis. Psychiatry Res. 2015; 228(2): 197-202. DOI:10.1016/j.psychres.2015.04.027.

Ugalde Olano A, Egia A, Fernandez Ruiz S, Loizaga Iriarte A, Zuniga Garcia P, Garcia S, et al. Methodological aspects of the molecular and histological study of prostate cancer: Focus on PTEN. Methods. 2015; 77-78: 25-30. DOI:10.1016/j.ymeth.2015.02.005.

Lopez S, Smith Zubiaga I, Garcia de Galdeano A, Dolores Boyano M, Garcia O, Gardeazabal J, et al. Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation. PLoS One. 2015; 10(8). DOI:10.1371/journal.pone.0134911.

Peckova K, Martinek P, Ohe C, Kuroda N, Bulimbasic S, Condom Mundo E, et al. Chromophobe renal cell carcinoma with neuroendocrine and neuroendocrine-like features. Morphologic, immunohistochemical, ultrastructural, and array comparative genomic hybridization analysis of 18 cases and review of the literature. Ann Diagn Pathol. 2015; 19(4): 261-268. DOI:10.1016/j.anndiagpath.2015.05.001.

Peckova K, Ohe C, Kuroda N, Martinek P, Bulimbasic S, Montiel DP, et al. Chromophobe Renal Cell Carcinoma With Neuroendocrine Differentiation and Neuroendocrine-Like Features. Morphologic, Immunohistochemical, Ultrastructural, and ArrayCGH Analysis of 18 Cases. Mod Pathol. 2015; 28(2): 250-250

Ruiz de Garibay G, Herranz C, Llorente A, Boni J, Serra Musach J, Mateo F, et al. Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness. PLoS One. 2015; 10(7). DOI:10.1371/journal.pone.0132546.

Amo L, Tamayo Orbegozo E, Maruri N, Buque A, Solaun M, Rinon M, et al. Podocalyxin-like protein 1 functions as an immunomodulatory molecule in breast cancer cells. Cancer Lett. 2015; 368(1): 26-35. DOI:10.1016/j.canlet.2015.06.029.

Urizar I, Munoa I, Gianzo M, Estomba H, Matorras R, Exposito A, et al. The Kappa-opioid receptor modulates the human sperm capacitation and acrosome reaction. Hum Reprod. 2015; 30(1): 174-175

Munoa I, Urizar I, Casis L, Irazusta J, Subiran N. The Epigenetic Regulation of the Opioid System: New Individualized Prompt Prevention and Treatment Strategies. J Cell Biochem. 2015; 116(11): 2419-2426. DOI:10.1002/jcb.25222.

Carrascosa JM, Belinchón I, De Cueva P, Izu R, Luelmo J, Ruiz Villaverde R. Recomendaciones de expertos para el tratamiento de la psoriasis en situaciones especiales. Actas Dermosifiliogr. 2015; 106(4): 292-309. DOI:10.1016/j.ad.2014.11.005.

Lawrie CH, Larrea E, Larrinaga G, Goicoechea I, Arestin M, Fernandez Mercado M, et al. Targeted next-generation sequencing and non-coding RNA expression analysis of clear cell papillary renal cell carcinoma suggests distinct pathological mechanisms from other renal tumour subtypes. J Pathol. 2014; 232(1): 32-42. DOI:10.1002/path.4296.

Mendieta Eckert M, Ratón Nieto JA, Santiago Villate Á. Shoe dermatitis. Med Clin. 2014; 142(9): 422-423. DOI:10.1016/j.medcli.2013.06.018.

Ashour N, Angulo JC, Andres G, Alelu R, Gonzalez Corpas A, Toledo MV, et al. A DNA Hypermethylation Profile Reveals New Potential Biomarkers for Prostate Cancer Diagnosis and Prognosis. Prostate. 2014; 74(12): 1171-1182. DOI:10.1002/pros.22833.

De Quintana Sancho A, Antonio Raton J, Eizaguirre X. Occupational allergic contact dermatitis caused by N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propionate in a dental assistant. Contact Dermatitis. 2014; 70(6): 379-380. DOI:10.1111/cod.12174.

Blanco L, Sanz B, Perez I, Sanchez CE, Luz Candenas M, Pinto FM, et al. Altered glutamyl-aminopeptidase activity and expression in renal neoplasms. BMC Cancer. 2014; 14. DOI:10.1186/1471-2407-14-386.

Rios P, Nunes Xavier CE, Tabernero L, Koehn M, Pulido R. Dual-Specificity Phosphatases as Molecular Targets for Inhibition in Human Disease. Antioxid Redox Signal. 2014; 20(14): 2251-2273. DOI:10.1089/ars.2013.5709.

Arroyo Berdugo Y, Alonso S, Ribas G, Ibarrola Villava M, Pena Chilet M, Martinez Cadenas C, et al. Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma. PLoS One. 2014; 9(4). DOI:10.1371/journal.pone.0095522.

Castillejo A, Sanchez Heras AB, Egoavil C, Esquembre C, Castillejo M, Martinez Canto A, et al. Colorectal Cancer in Hereditary Leiomyomatosis and Renal Cell Carcionoma Syndrome (HLRCC). Lab Invest. 2014; 94(1): 470-470

Alseda M, Godoy P, Gardeazabal J, Angels Borras M. Community outbreak of Pseudomonas aeruginosa folliculitis associated with a spa. Med Clin. 2014; 142(2): 86-87. DOI:10.1016/j.medcli.2013.06.027.

Larrinaga G, Perez I, Blanco L, Sanz B, Errarte P, Beitia M, et al. Prolyl Endopeptidase Activity Is Correlated with Colorectal Cancer Prognosis. Int J Med Sci. 2014; 11(2): 199-208. DOI:10.7150/ijms.7178.

Castillejo A, Sanchez Heras AB, Egoavil C, Esquembre C, Castillejo M, Martinez Canto A, et al. Colorectal Cancer in Hereditary Leiomyomatosis and Renal Cell Carcionoma Syndrome (HLRCC). Mod Pathol. 2014; 27(2): 470-470

Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin Sang ID, et al. A Unified Nomenclature and Amino Acid Numbering for Human PTEN. Sci Signal. 2014; 7(332). DOI:10.1126/scisignal.2005560.

Garcia Tello A, Angulo JC, Rodriguez Ubreva J, Andres G, Lopez JI, Sanchez Chapado M, et al. Prostate anatomy in motheaten viable (me(v)) mice with mutations in the protein tyrosine phosphatase SHP-1. Actas Urol Esp. 2014; 38(7): 438-444. DOI:10.1016/j.acuro.2014.02.005.

Lopez S, Garcia O, Yurrebaso I, Flores C, Acosta Herrera M, Chen H, et al. The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population. PLoS One. 2014; 9(8). DOI:10.1371/journal.pone.0104367.

Santos Concejero J, Tam N, Granados C, Irazusta J, Bidaurrazaga Letona I, Zabala Lili J, et al. Interaction Effects of Stride Angle and Strike Pattern on Running Economy. Int J Sports Med. 2014; 35(13): 1118-1123. DOI:10.1055/s-0034-1372640.

Kuroda N, Ohe C, Kawakami F, Mikami S, Furuya M, Matsuura K, et al. Clear cell papillary renal cell carcinoma: a review. Int J Clin Exp Pathol. 2014; 7(11): 7312-7318

Corominas Cishek A, Gonzalez M, Caamano V, Andueza E, Cerda N, Lopez JI. Biphasic alveolo-squamoid renal carcinoma (BASRC): Light and immunohistochemical study of 3 cases. Virchows Arch. 2014; 465(1): 157-157

Lopez JI, Caceres F, Perez A, Caamano V, Larrinaga G, Lecumberri D, et al. Diagnostic Usefulness of the Cytological Study of the Transport Buffer in Transrectal Prostate Core Biopsies. Actas Urol Esp. 2014; 38(9): 566-570. DOI:10.1016/j.acuro.2014.01.003.

Garcia Tello A, Ramon de Fata F, Andres G, Ropero S, Lopez JI, Angulo JC. DNA repair genes and prognosis in sporadic forms of urotheliat carcinoma of the upper urinary tract. Actas Urol Esp. 2014; 38(9): 600-607. DOI:10.1016/j.acuro.2014.03.010.

Garcia Tello A, Angulo JC, Andres G, Ramon de Fata F, Sanchez Chapado M, Lopez JI. Impact of p53, MIB-1 and PECAM-1 expression on the prognosis of urothelial carcinoma of the renal pelvis. Actas Urol Esp. 2014; 38(8): 506-514. DOI:10.1016/j.acuro.2014.02.015.

Santos Concejero J, Tucker R, Granados C, Irazusta J, Bidaurrazaga Letona I, Zabala Lili J, et al. Influence of regression model and initial intensity of an incremental test on the relationship between the lactate threshold estimated by the maximal-deviation method and running performance. J Sports Sci. 2014; 32(9): 853-859. DOI:10.1080/02640414.2013.862844.

Santos Concejero J, Tam N, Granados C, Irazusta J, Bidaurrazaga Letona I, Zabala Lili J, et al. STRIDE ANGLE AS A NOVEL INDICATOR OF RUNNING ECONOMY IN WELL-TRAINED RUNNERS. J Strength Cond Res. 2014; 28(7): 1889-1895. DOI:10.1519/JSC.0000000000000325.

Santos Concejero J, Granados C, Irazusta J, Bidaurrazaga Letona I, Zabala Lili J, Tam N, et al. OBLA is a better predictor of performance than Dmax in long and middle-distance well-trained runners. J Sports Med Phys Fit. 2014; 54(5): 553-558

Pérez Ferriols A, Aguilera J, Aguilera P, de Argila D, Barnadas MA, de Cabo X, et al. Determination of minimal erythema dose and anomalous reactions to UVA radiation by skin phototype. Actas Dermosifiliogr. 2014; 105(8): 780-788. DOI:10.1016/j.ad.2014.05.001.

Cerda N, Planelles M, Macias L, Bulimbasic S, Peiro G, Robles A, et al. Urinary tract Perivascular Epithelioid Cell tumour (PEComa): Clinical, histological, and immunohistochemical study of Rheb/mTOR/p70s6k cascade in 9 cases. Virchows Arch. 2014; 465(1): 161-161

Caamano Villaverde V, Lopez JI, Andueza E, Gonzalez M, Cerda N, Corominas A, et al. Tubular renal cell carcinoma with prominent cytoplasmic vacuolization: Report of two cases of a previously non described phenotype. Virchows Arch. 2014; 465(1): 263-264

Corominas Cishek A, Guarch R, Erramuzpe A, Zaldumbide L, Cerda N, Andueza E, et al. Parameters predicting intratumor heterogeneity in clear cell renal cell carcinoma. Virchows Arch. 2014; 465(1): 158-158

Zarrazquin I, Torres Unda J, Ruiz F, Irazusta J, Kortajarena M, Hoyos Cillero I, et al. Longitudinal study: lifestyle and cardiovascular health in health science students. Nutr Hosp. 2014; 30(5): 1144-1151. DOI:10.3305/nh.2014.30.5.7833.

Navajas B, Gardeazabal J, Antonio Raton J, Agesta N, Eizaguirre X. Retrospective analysis of the efficacy and safety of adalimumab 40 mg e.o.w. in patients with moderate to severe plaque psoriasis in a range of treatment duration from 4 to 52 months. J Am Acad Dermatol. 2014; 70(5): 183-183

Perez A, Loizaga A, Arceo R, Lacasa I, Rabade A, Zorroza K, et al. A Pilot Study on the Potential of RNA-Associated to Urinary Vesicles as a Suitable Non-Invasive Source for Diagnostic Purposes in Bladder Cancer. Cancers (Basel). 2014; 6(1): 179-192. DOI:10.3390/cancers6010179.

Portillo JA, Madero R, Solsona E, Fernandez JM, Martínez Piñeiro L, Palou J, et al. Influence of the true number of Bacillus Calmette-Guerin instillations on the prognosis of non-muscle invasive bladder tumors. Actas Urol Esp. 2014; 38(5): 280-284. DOI:10.1016/j.acuro.2013.10.010.

Lopez JI, Guarch R, Larrinaga G, Corominas-Cishek A, Orozco R. Cell heterogeneity in clear cell renal cell carcinoma. APMIS. 2013;121:1187-91. FI: 2,068(Q2)

López JI, Schiavo-Lena M, Corominas-Cishek A, Yagüe A, Bauleth K, Guarch R, et al. Nephrogenic adenoma of the urinary tract: clinical, histological, and immunohistochemical characteristics. Virchows Arch. 2013;463:819-25. FI: 2,676(Q2)

Larrinaga G, Perez I, Ariz U, Sanz B, Beitia M, Errarte P, et al. Clinical impact of aspartylaminopeptidase expression and activity in colorectal cancer. Transl Res. 2013;162:297-308. FI: 3,490(Q1)

Cejudo-Roman A, Pinto FM, Subiran N, Ravina CG, Fernandez-Sanchez M, Perez-Hernandez N,  et al. The Voltage-Gated Sodium Channel Na(v)1.8 Is Expressed in Human Sperm. PLoS One. 2013;8:e76084  FI: 3,730(Q1)

Corominas-Cishek A, Schiavo-Lena M, Macias L, Yaguee A, Guarch R, Tardanico R, et al. Nephrogenic adenoma/metaplasia: A multicenter clinicopathological study of 106 cases. Virchows Arch. 2013;463:123. FI: 2,676(Q2). ( Meeting Abstract).

Corominas-Cishek A, Gonzalez M, Perez A, Caamano V, Muniz G, Cerda N, et al. BRAF V600E mutation is associated with aggressive behaviour in the papillary variant of papillary thyroid carcinoma. Virchows Arch. 2013;463:152. FI: 2,676(Q2). ( Meeting Abstract).

Caamano Villaverde V, Schiavo-Lena M, Yaguee A, Zaldumbide L, Guarch R, Tardanico R, et al Metastases into renal cell carcinomas.Virchows Arch. 2013;463:331-2. FI: 2,676(Q2). ( Meeting Abstract)

Caamano Villaverde V, Muniz G, Corominas-Cishek A, Cerda N, Perez A, Gonzalez M, et al. Nodular adenocarcinoma of the prostate with leiomyomatousstroma: Report of 3 cases of an underecognized histological phenotype. Virchows Arch. 2013;463:331.  FI: 2,676(Q2). ( Meeting Abstract)

Cerda N, Corominas-Cishek  A, Muniz G, Caamano V, Perez A, Gonzalez M, et al. Nested variant of urothelial carcinoma: Report of 2 cases. Virchows Arch. 2013;463:349. FI: 2,676(Q2). ( Meeting Abstract)

Larrinaga G, Sanz B, Blanco L, Perez I, Candenas ML, Pinto FM, et al. Cannabinoid CB1 receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma. Clin Biochem. 2013;46:638-41. FI: 2,076(Q2).

López JI. Renal tumors with clear cells.A review. Pathol Res Pract. 2013;209:137-46. FI: 1,213(Q4)

Nunes-Xavier CE, Martín-Pérez J, Elson A, Pulido R. Protein tyrosine phosphatases as novel targets in breast cancer therapy. Biochim Biophys Acta. 2013;1836:211-26. FI: 9,033(Q1)

Pulido R, Stoker AW, Hendriks WJ. PTPs emerge as PIPs: protein tyrosine phosphatases with lipid-phosphatase activities in human disease. Hum Mol Genet. 2013;22:R66-76 FI: 7,692(Q1)

Berthier A, Jiménez-Sáinz J, Pulido R. PINK1 regulates histone H3 trimethylation and gene expression by interaction with the polycomb protein EED/WAIT1. Proc Natl Acad Sci USA. 2013;110:14729-34. FI: 9,737(Q1)

Tesis del grupo

Autor/a: Ana Sánchez Díez. Título: Marcadores genéticos de susceptibilidad y pronóstico del melanoma cutáneo. Directores/as: María Dolores Boyano López, Santos Alonso Alegre.

Autor/a: Leire Torices Cabarcos. Título: Premature termination codons as a source of proteoform diversity in PTEN, VHL and MMADHC genes: relevance of premature termination codon readthrough based therapy. Directores/as: Rafael Pulido Murillo. URL: http://hdl.handle.net/10810/59595.

Autor/a: Andrea Agüera Lorente. Título: Implicación de proteínas contenidas en vesículas extracelulares en la modulación del microambiente tumoral del melanoma cutáneo y análisis de su potencial como biomarcadores de pronóstico temprano. Directores/as: Aintzane Apraiz García, Aintzane Asumendi Mallea. URL: http://hdl.handle.net/10810/62140.

Autor/a: Sandra Luna Blanco. Título: Análisis funcional y de reconstitución traduccional de mutaciones hereditarias del gen PTEN en pacientes con síndromes tumorales y de autismo. Directores/as: Dr. Rafael Pulido Murillo. URL: http://hdl.handle.net/10810/57171.

Autor/a: Alexander Ferro Uriguen. Título: Pertsona ardatz duen preskripzio eredu baten eragina bizitzaren amaieran ospitaleratuta dauden paziente geriatrikoetan. Directores/as: Dr. Francisco Javier Gil Goicouria. URL: http://hdl.handle.net/10810/54340.

Autor/a: María Muñoa Capron-Manieux. Título: Efectividad de la educación en neurociencia del dolor frente a las terapias habituales para el abordaje de la fibromialgia. Intervención grupal estructurada en atención primaria. Directores/as: Dr. Gorka Larrinaga Embeitia, Dra. Eunate Arana Arri. URL: http://hdl.handle.net/10810/53521.

Autor/a: Nere Mendizabal Gallastegui. Título: Desigualdades sociales en la cobertura y participación en el Programa de Cribado de Cáncer Colorrectal de Euskadi. Directores/as: Dra. María Isabel Portillo Villares. URL: http://hdl.handle.net/10810/54268.

Autor/a: Nuria Revilla Gómez. Título: Influencia de los factores de riesgo cardiovascular en la Enfermedad de Alzheimer preclínica. Directores/as: Dr. Francisco Javier Gil Goicouria. URL: http://hdl.handle.net/10810/54796.

Autor/a: Ana Loizaga Iriarte. Título: Diseño y explotación de un circuito de investigación traslacional en cáncer de próstata. Directores/as: Dr. Arkaitz Carracedo Pérez. URL: http://hdl.handle.net/10810/51692.

Autor/a: María del Pilar García Gil. Título: Evaluación de características antropométricas y de la condición física de jugadoras de baloncesto de alto nivel y de jugadoras en proceso de desarrollo. Directores/as: Dr. Francisco Javier Gil Goicouria, Dr. Juan José Torres Unda. URL: http://hdl.handle.net/10810/48663.

Autor/a: Arantza Pérez Valle. Título: Lipidomics in melanoma: identification of new lipid prognostic biomarkers. Directores/as: Dra. Aintzane Asumendi Mallea, Dra. María Dolores Boyano López. URL: http://hdl.handle.net/10810/49976.

Autor/a: Haritz Arrieta Etxeberria. Título: "Ariketa fisikoaren eragina adineko pertsonen hauskortasunari lotutako parametroetan / Effects of physical exercise on frailty-related parameters in older adults". Directores/as: Dr. Jon Irazusta Astiazaran, Dra. Ana Rodríguez Larrad.

Autor/a: Itziar Urizar Arenaza . Título: "Proteomic study of sperm-specific molecular mechanisms in human spermatozoa underlying sperm fertility/Giza espermatozoideen ahalmen ugalkorra erregulatzen duten mekanismo molekular espezifikoen azterketa proteomikoa.". Directores/as: Dr. Jon Irazusta Astiazaran, Dra. Nerea Subiran Ciudad.

Autor/a: Iraia Muñoa Hoyos. Título: "Study of the epigenetic cellular memory induced by morphine: a next generation sequencing approach/Morfinak eragindako zelulen arteko memoria epigenetikoaren azterketa, bigarren belaunaldiko sekuentziazioaren bitartez". Directores/as: Dr. Jon Irazusta Astiazaran , Dra. Nerea Subiran Ciudad.

Autor/a: María Victoria Rodríguez Gallego. Título: "Estudio del metabolismo peptídico folicular y su relación con la fertilidad". Directores/as: Dr. Luis Casis Sáenz, Dra. Juana Hernández Hernández.

Autor/a: Janire Mingo Gómez de Oteo. Título: "Caracterización molecular de epítopos de la región C-terminal de PTEN y análisis funcional de mutaciones tumorales N-terminales: validación en cánceres genitourinarios". Director/a: Dr. Rafael Pulido Murillo.

Autor/a: María José Fernández Landa, . Título: "Evaluación de la calidad de la colonoscopia de cribado en el programa de cribado de cáncer colorrectal en la CAPV". Directores/as: Dra. Amaia Bacigalupe de la Hera, Dra. Isabel Portillo Villares.

Autor/a: Mª Isabel Idigoras Rubio. Título: "Evaluación a nivel poblacional del beneficio en salud y costes del programa de detección precoz del cáncer de colon y recto en la CAPV". Directores/as: Dr. Luis Carlos Abecia Inchaurregui, Dr. Iñaki Gutiérrez Ibarluzea.

Autor/a: María Victoria Aparicio Prieto. Título: "Fragmentación del ADN espermático y su relación con el metabolismo peptídico". Directores/as: Dr. Luis Casis Saenz, Dra. Nerea Subirán Ciudad.

Autor/a: Laura Zaldumbide Dueñas. Título: La heterogeneidad intratumoral en el carcinoma renal de células claras. Director/a: Dr. Jose Ignacio López Fernández de Villaverde. UPV/EHU

Autor/a: Pedro Varela Gonzalez. Título: Actividad y expresión de enzimas convertidoras de angiotensina en neoplasias renales. Director/a: Dr. José Ignacio López Fernández de Villaverde, Dr. Gorka Larrinaga Embeitia. UPV/EHU

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