Unidad de cuidados Intensivos de pediatría
Actividades del grupo
Centrando sus tareas de investigación en el estudio de la patología crítica, epidemiología y fisiopatología, clínica, mejora de los métodos diagnósticos o aplicación de nuevas terapéuticas.
Nuestro campo de investigación más factible es la clínica, participando en estudios de carácter multicéntrico, prospectivos, aleatorizados y controlados en colaboración con otras Unidades de similares características a la nuestra para obtener unos resultados con mayor nivel de evidencia.
Las líneas de investigación desarrolladas son:
Seguridad del paciente
Coordinador: Manuel Nieto Faza.
Evaluación de la percepción sobre seguridad del paciente en una Unidad de Cuidados Intensivos de Pediatría según el cuestionario de la "Agency for Healthcare Research and Quality" (AHRQ) adaptado a nuestro medio.
Investigación y análisis de los incidentes notificados en una Unidad de Cuidados Intensivos de Pediatría según el Protocolo de Londres. Elaboración de informes con recomendaciones.
Sepsis y Síndromes Hemofagociticos
Coordinador: Javier Pilar.
Estudio sobre identificación de nuevos biomarcadores de inflamación y activación linfomonocitaria para desarrollar nuevas herramientas diagnósticas en las sepsis graves y síndromes hemogagocíticos y síndromes hemofagocíticos.
Red Europea para Síndrome de Hipoventilación Central, optimizando el cuidado de los pacientes
Coordinador: Diego García Urabayen.
El Registro del Síndrome de Hipoventilación Central (SHC), es un programa que recoge los datos globales de los pacientes con SHC. Uno de sus objetivos es desarrollar investigación específica, herramientas diagnósticas y nuevos métodos terapéuticos de los pacientes.
Infeccioso
Coordinador: Elvira Morteruel.
VINCIP-SECIP. Estudio multicéntrico sobre la Infección Nosocomial en la Unidad de Cuidados Intensivos Pediatría, cuyo objetivo es disponer de un modelo de vigilancia y control de la infección nosocomial común para todos los hospitales.
ABISS Edusepsis Pediátrico. Estudio prospectivo, multicéntrico con un diseño antes/después de una intervención múltiple de traslación del conocimiento. Su objetivo principal es evaluar el impacto de una intervención múltiple de traslación del conocimiento dirigida a mejorar la antibioticoterapia empírica de la sepsis grave en la mortalidad.
Cardiopatías Congénitas
Coordinador: Silvia Redondo.
Enfermedades Respiratorias y Ventilación Mecánica
Coordinador: Y. López Fernández.
PEDALIEN: Estudio multicéntrico sobre la incidencia y pronóstico del Síndrome de distrés respiratorio agudo en la población pediátrica española.
NIVNAVAPED: Ensayo clínico multicéntrico, randomizado, sobre ventilación no invasiva: NAVA (neurally adjusted ventilatory assist) vs. Presión soporte en el fracaso respiratorio agudo pediátrico.
PANDORA: Insuficiencia respiratoria aguda hipoxemica.
LONGVENTKIDS. Pacientes en ventilación mecánica prolongada.
Coordinador/a del grupo
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Yolanda Margarita López Fernández
Coordinador de grupo
yolandamargarita.lopezfernandez@osakidetza.eus
CV resumen
Publicaciones del grupo
Iyer N, Khemani R, Emeriaud G, Lopez Fernandez YM, Korang SK, Steffen KM, et al. Methodology of the Second Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2023; 24(Supplement 1 2S): 76-86. DOI:10.1097/PCC.0000000000003160.
Emeriaud G, Lopez Fernandez YM, Iyer NP, Bembea MM, Agulnik A, Barbaro RP, et al. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2). Pediatr Crit Care Med. 2023; 24(2): 143-168. DOI:10.1097/PCC.0000000000003147.
Abu Sultaneh S, Iyer NP, Fernandez A, Gaies M, Gonzalez Dambrauskas S, Hotz JC, et al. Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Document. Am J Respir Crit Care Med. 2023; 207(1): 17-28. DOI:10.1164/rccm.202204-0795SO.
Solana MJ, Slocker M, de Companon ZM, Olmedilla M, Minambres M, Reyes S, et al. Prevalence, Risk Factors and Impact of Nutrition Interruptions in Critically Ill Children. Nutrients. 2023; 15(4). DOI:10.3390/nu15040855.
Martinez Dubarbie F, Rollan Herrera M. Peripheral nervous system involvement in Q fever. Acta Neurol Belg. 2022; 122(1): 17-22. DOI:10.1007/s13760-021-01791-2.
Pilar Orive FJ, Astigarraga I, Azkargorta M, Elortza F, Garcia Obregon S. A Three-Protein Panel to Support the Diagnosis of Sepsis in Children. J Clin Med. 2022; 11(6). DOI:10.3390/jcm11061563.
Butragueno Laiseca L, Martin GM, Cortes RG, Galan CR, de Marigorta ZMDM, Anton JG, et al. Multicenter randomized clinical trial comparing dexamethasone versus placebo in preventing upper airway obstruction after extubation in critically ill children. Sci Rep. 2022; 12(1). DOI:10.1038/s41598-022-08178-0.
Arrieta H, Rezola Pardo C, Gil J, Kortajarena M, Zarrazquin I, Echeverria I, et al. Effects of an individualized and progressive multicomponent exercise program on blood pressure, cardiorespiratory fitness, and body composition in long-term care residents: Randomized controlled trial. Geriatr Nurs. 2022; 45: 77-84. DOI:10.1016/j.gerinurse.2022.03.005.
Argudo E, Hernandez Tejedor A, Belda Hofheinz S, Fuset MP, Sanchez Galindo A, Burgueno P, et al. Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Spanish Society of Pediatric Intensive Care (SECIP) consensus recommendations for ECMO transport. Med Intensiva (Engl Ed). 2022; 46(8): 446-454. DOI:10.1016/j.medine.2022.06.005.
Fresan Ruiz E, Izurieta Pacheco AC, Girona Alarcon M, de Carlos Vicente JC, Bustinza Arriortua A, Slocker Barrio M, et al. Antimicrobial Stewardship Improvement in Pediatric Intensive Care Units in Spain-What Have We Learned?. Children-Basel. 2022; 9(6). DOI:10.3390/children9060902.
Rollan Herrera M, Kerexeta Sarriegi J, Gil Anton J, Pilar Orive J, Macia Oliver I. K-Means Clustering for Shock Classification in Pediatric Intensive Care Units. Diagnostics. 2022; 12(8). DOI:10.3390/diagnostics12081932.
Abu Sultaneh S, Iyer NP, Fernandez A, Gaies M, Gonzalez Dambrauskas S, Hotz JC, et al. Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A PALISI Network Document. Am J Respir Crit Care Med. 2022. DOI:10.1164/rccm.202204-0795OC.
Iyer NP, Lopez Fernandez YM, Gonzalez Dambrauskas S, Baranwal AK, Hotz JC, Zhu M, et al. A Network Meta-analysis of Dexamethasone for Preventing Post-Extubation Upper Airway Obstruction in Children. Ann Am Thorac Soc. 2022; 20(1): 118-130. DOI:10.1513/AnnalsATS.202203-212OC.
Rollan Martinez Herrera M, Gonzalez Urdiales P, Zubizarreta Zamalloa A, Rodriguez Merino E, Martinez Dubarbie F. Central nervous system infection by Bacillus cereus: a case report and literature review. Rev Neurologia. 2022; 75(8): 239-245. DOI:10.33588/rn.7508.2021412.
Solana MJ, Manrique G, Slocker M, Fernandez R, Gil R, Yun C, et al. Early vs late enteral nutrition in pediatric intensive care unit: Barriers, benefits, and complications. Nutrition In Clinical Practice : Official Publication Of The American Society For Parenteral And Enteral Nutrition. 2022. DOI:10.1002/ncp.10922.
Menchaca M, Astigarraga I, De la Serna MJL, Marcos C, Martin P, Sanz I, et al. IMPLEMENTATION OF A PEDIATRIC EARLY WARNING SYSTEM (PEWS) IN A PEDIATRIC ONCOLOGY UNIT OF A SPANISH HOSPITAL: ADVANTAGES AND LIMITATIONS. Pediatr Blood Cancer. 2022; 69: 548-549
Tagarro A, Dominguez Rodriguez S, Miguel Mesa J, Epalza C, Grasa C, Isabel Iglesias Bouzas M, et al. Treatments for multi-system inflammatory syndrome in children - discharge, fever, and second-line therapies. Eur J Pediatr. 2022; 182(1): 461-466. DOI:10.1007/s00431-022-04649-8.
Kneyber MCJ, Khemani RG, Bhalla A, Blokpoel RGT, Cruces P, Dahmer MK, et al. Understanding clinical and biological heterogeneity to advance precision medicine in paediatric acute respiratory distress syndrome. Lancet Resp Med. 2022; 11(2): 197-212. DOI:10.1016/S2213-2600(22)00483-0.
Abu Sultaneh S, Iyer NP, Fernandez A, Gaies M, Gonzalez Dambrauskas S, Hotz JC, et al. Operational Definitions Related to Pediatric Ventilator Liberation. Chest. 2022. DOI:10.1016/j.chest.2022.12.010.
Solana MJ, Manrique G, Fernandez R, Slocker M, Garcia M, Redondo S et al. Nutritional status and nutrition support in critically ill children in Spain: Results of a multicentric study. Nutrition. 2021; 84. DOI:10.1016/j.nut.2020.110993.
Bhalla AK, Klein MJ, Emeriaud G, Lopez Fernandez YM, Napolitano N, Fernandez A et al. Adherence to Lung-Protective Ventilation Principles in Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2021; 49(10): 1779-1789. DOI:10.1097/CCM.0000000000005060.
Martinez Dubarbie F, Ortega Valin F, Gonzalez Quintanilla 5TH, Garcia Poza J, Feo Gonzalez M, Marcos Gonzalez S et al. Fatal case of simply influenza A (H3N2)-associated encephalitis in immunocompetent patient. Clin Neurol Neurosurg. 2021; 210: 106956-106956. DOI:10.1016/j.clineuro.2021.106956.
Lopez Fernandez YM, Martinez Azagra A, Gonzalez Gomez JM, Perez Caballero Macarron C, Garcia Gonzalez M, Parrilla J et al. Acute Hypoxemic Respiratory Failure in Children at the Start of COVID-19 Outbreak: A Nationwide Experience. J Clin Med. 2021; 10(19). DOI:10.3390/jcm10194301.
Astigarraga I, De Heras J, Perez Estevez E, Lopez Bayon J, Garcia Obregon S, Aldamiz Echevarria L. LONG TERM SURVIVAL AFTER EARLY ONSET LYSOSOMAL ACID LIPASE DEFICIENCY PRESENTING AS HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS AND BENEFIT OF ENZYMATIC REPLACEMENT TREATMENT WITH SEBELIPASE ALFA IN 2 PATIENTS. Pediatr Blood Cancer. 2020; 67: 2-3
Arrieta H, Rezola Pardo C, Kortajarena M, Hervas G, Gil J, Yanguas JJ, et al. The impact of physical exercise on cognitive and affective functions and serum levels of brain-derived neurotrophic factor in nursing home residents: A randomized controlled trial. Maturitas. 2020; 131: 72-77. DOI:10.1016/j.maturitas.2019.10.014.
Rowan CM, Klein MJ, Hsing DD, Dahmer MK, Spinella PC, Emeriaud G, et al. Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study. Am J Respir Crit Care Med. 2020; 201(11): 1389-1397. DOI:10.1164/rccm.201909-1807OC.
Yehya N, Harhay MO, Klein MJ, Shein SL, Piñeres Olave BE, Izquierdo L, et al. Predicting Mortality in Children With Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2020; 48(6): 514-522. DOI:10.1097/CCM.0000000000004345.
Lopez Fernandez YM, Smith LS, Kohne JG, Weinman JP, Modesto Alapont V, Reyes Dominguez SB, et al. Prognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study. Intensive Care Med. 2020; 46(7): 1382-1393. DOI:10.1007/s00134-020-06074-7.
Gil Anton J, Mielgo VE, Rey Santano C, Galbarriatu L, Santos C, Unceta M, et al. Addition of terlipressin to initial volume resuscitation in a pediatric model of hemorrhagic shock improves hemodynamics and cerebral perfusion. PLoS One. 2020; 15(7). DOI:10.1371/journal.pone.0235084.
Garcia Salido A, de Carlos Vicente JC, Belda Hofheinz S, Balcells Ramirez J, Slocker Barrio M, Leoz Gordillo I, et al. Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain. Crit Care. 2020; 24(1): 666-666. DOI:10.1186/s13054-020-03332-4.
Lopez J, Pons Odena M, Medina A, Molinos Norniella C, Palanca Arias D, Demirkol D, et al. Early factors related to mortality in children treated with bi-level noninvasive ventilation and CPAP. Pediatr Pulmonol. 2020; 56(5): 1237-1244. DOI:10.1002/ppul.25246.
Khemani RG, Smith L, Lopez Fernandez YM, Kwok J, Morzov R, Klein MJ, et al. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. Lancet Resp Med. 2019; 7(2): 115-128. DOI:10.1016/S2213-2600(18)30344-8.
Astigarraga I, Garcia Obregon S, Alba Pavon P, Seijas I, Pilar Orive J, Borrego F, et al. THE ROLE IN DIAGNOSIS OF HIGH SERUM LEVELS OF sCD25 AND sCD163 IN PATIENTS WITH SEVERE SEPSIS AND HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH). Pediatr Blood Cancer. 2019; 66(1): 1-1
Cano Garcinuno A, Praena Crespo M, Mora Gandarillas I, Carvajal Uruena I, Teresa Callen Blecua M, Garcia Merino A, et al. Criteria heterogeneity in the diagnosis of acute bronchiolitis in Spain. An Pediatr. 2019; 90(2): 109-117. DOI:10.1016/j.anpedi.2018.07.004.
Pilar Orive J, Modesto i Alapont V. High-flow oxygen therapy: Non-invasive respiratory support goes out of the PICU. Is it an efficient alternative?. An Pediatr. 2019; 90(2): 69-71. DOI:10.1016/j.anpedi.2018.11.004.
Khemani RG, Smith L, Lopez Fernandez YM. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study (vol 7, pg 115, 2019). Lancet Resp Med. 2019; 7(3): 12-12
Khemani RG, Smith L, Lopez Fernandez YM. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study (vol 7, pg 115, 2019). Lancet Resp Med. 2019; 7(2): 9-9
Agra Tunas MC, Pilar Orive FJ, Rodriguez Merino E, Lopez Herce Cid J, Manrique Martin G, Garcia Casas P, et al. Modes of dying of children in Intensive Care Units in Spain: MOMUCIP study. An Pediatr. 2019; 91(4): 228-236. DOI:10.1016/j.anpede.2019.01.012.
Rodríguez Rey R, Palacios A, Alonso Tapia J, Pérez E, Álvarez E, Coca A, et al. Are Pediatric Critical Personnel Satisfied With Their Lives? Prediction of Satisfaction With Life From Burnout, Posttraumatic Stress, and Posttraumatic Growth, and Comparison With Noncritical Pediatric Staff. Pediatr Crit Care Med. 2019; 20(3). DOI:10.1097/PCC.0000000000001861.
Bonfill X, Quintana MJ, Bellmunt S, Suclupe S, Gómez E, Fernandez de Valderrama I, et al. Descriptive and follow-up study of patients treated surgically for abdominal aortic aneurysm at tertiary hospitals in Spain. Int Angiol. 2019; 38(5): 402-409. DOI:10.23736/S0392-9590.19.04206-8.
Yunge M, Cordero J, Martinez D, Bustos R, Wegner A, Castro M, et al. Effectiveness of Two Targeted Temperature Management Methods After Pediatric Postcardiac Arrest: A Multicenter International Study. Pediatr Crit Care Med. 2019; 20(2): 77-82. DOI:10.1097/PCC.0000000000001813.
Lopez Herce Cid J, Delgado AF, Munoz Benavides E, Coss Bu JA, Iramain R, Valdez Villaruel S, et al. The Latin American and Spanish Survey on Nutrition in Pediatric Intensive Care (ELAN-CIP2). Pediatr Crit Care Med. 2019; 20(1): 23-29. DOI:10.1097/PCC.0000000000001761.
Garcia Obregon S, Azkargorta M, Seijas I, Pilar Orive J, Borrego F, Elortza F, et al. Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients. J Microbiol Immunol Infect. 2018; 51(4): 465-472. DOI:10.1016/j.jmii.2016.12.002.
Sanz B, Larrinaga G, Fernandez Atucha A, Gil J, Fraile Bermudez AB, Kortajarena M, et al. Obesity parameters, physical activity, and physical fitness are correlated with serum dipeptidyl peptidase IV activity in a healthy population. Heliyon. 2018; 4(5). DOI:10.1016/j.heliyon.2018.e00627.
de la Oliva P, Cambra Lasaosa FJ, Quintana Diaz M, Rey Galan C, Sanchez Diaz JI, Martin Delgado MC, et al. Admission, discharge and triage guidelines for paediatric intensive care units in Spain. An Pediatr. 2018; 88(5): 287-287. DOI:10.1016/j.anpedi.2017.10.008.
de la Oliva P, Cambra Lasaosa FJ, Quintana Diaz M, Rey Galan C, Sanchez Diaz JI, Martin Delgado MC, et al. Admission, discharge and triage guidelines for paediatric intensive care units in Spain. Med Intensiv. 2018; 42(4): 235-246. DOI:10.1016/j.medin.2017.10.015.
Orive FJP, Lozano JB, Zuniga AL, Fernandez YML, Argaluza JE, Latour JM. Spanish translation and validation of the EMPATHIC-30 questionnaire to measure parental satisfaction in intensive care units. An Pediatr. 2018; 89(1): 50-57. DOI:10.1016/j.anpedi.2017.08.004.
Pilar J, Modesto I Alapont V, Lopez Fernandez YM, Lopez Macias O, Garcia Urabayen D, Amores Hernandez I. High-flow nasal cannula therapy versus non-invasive ventilation in children with severe acute asthma exacerbation: An observational cohort study. Med Intensiv. 2017; 41(7): 418-424. DOI:10.1016/j.medin.2017.01.001.
Esteban E, Belda S, García Soler P, Rodríguez Núñez A, Calvo C, Gil Anton J, et al. A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study. Intensive Care Med. 2017; 43(12): 1916-1918. DOI:10.1007/s00134-017-4721-4.
Astigarraga I, Garcia Obregon S, Gil Herrera J, Echebarria A, Adan R, Garcia Ariza M, et al. Early Onset of HLH and Inherited UNC13D and JAK3 Mutations in a Patient. A Difficult Diagnostic and Therapeutic Challenge. Pediatr Blood Cancer. 2017; 64(2): 1-2
Rodriguez Rey R, Palacios A, Alonso Tapia J, Perez E, Alvarez E, Coca A, et al. Posttraumatic Growth in Pediatric Intensive Care Personnel: Dependence on Resilience and Coping Strategies. Psychol Trauma. 2017; 9(4): 407-415. DOI:10.1037/tra0000211.
Astigarraga I, Garcia Obregon S, Capape S, Ortiz Calahorro J, Fernandez Bernal M, Pena A, et al. Prophylaxis and therapy of tumor lysis syndrome in 115 pediatric patients diagnosed with hematological neoplasms. Eur J Cancer. 2017; 72(1): 147-147. DOI:10.1016/S0959-8049(17)30557-9.
Garcia Obregon S, Seijas I, Pilar Orive J, Ruano C, Pena A, Zenarruzabeitia O, et al. High Levels of sCD25 and sCD163 in Patients Diagnosed with Sepsis. Could They be Useful for Sepsis Diagnosis and Differential Diagnosis with Hemophagocytic Lymphohistiocytosis (HLH)?. Pediatr Blood Cancer. 2016; 63(2): 42-42
Garcia Urabayen D, Lopez Fernandez YM, Pilar Orive J, Nieto Faza M, Gil Anton J, Lopez Bayon J, et al. Analysis of tracheostomies in a pediatric intensive care unit during the period 2003-2013. An Pediatr. 2016; 84(1): 18-23. DOI:10.1016/j.anpedi.2015.02.021.
Martinon Torres F, Png E, Khor CC, Davila S, Wright VJ, Sim KS, et al. Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies. Sci Rep. 2016; 6: 35842-35842. DOI:10.1038/srep35842.
Errarte P, Guarch R, Pulido R, Blanco L, Nunes Xavier CE, Beitia M, et al. The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases. PLoS One. 2016; 11(12). DOI:10.1371/journal.pone.0169105.
Torres Unda J, Zarrazquin I, Gravina L, Zubero J, Seco J, Gil SM, et al. Basketball Performance Is Related to Maturity and Relative Age in Elite Adolescent Players. J Strength Cond Res. 2016; 30(5): 1325-1332. DOI:10.1519/JSC.0000000000001224.
Larrinaga G, Perez I, Sanz B, Beitia M, Errarte P, Fernandez A, et al. Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis. PLoS One. 2015; 10(3). DOI:10.1371/journal.pone.0119436.
Fernandez Atucha A, Echevarria E, Larrinaga G, Gil J, Martinez Cengotitabengoa M, Gonzalez Pinto AM, et al. Plasma peptidases as prognostic biomarkers in patients with first-episode psychosis. Psychiatry Res. 2015; 228(2): 197-202. DOI:10.1016/j.psychres.2015.04.027.
Gil Anton J, Redondo S, Garcia Urabayen D, Nieto Faza M, Sanz I, Pilar J. Combined Cerebral and Renal Near-Infrared Spectroscopy After Congenital Heart Surgery. Pediatr Cardiol. 2015; 36(6): 1173-1178. DOI:10.1007/s00246-015-1139-z.
Quasney MW, Lopez Fernandez YM, Santschi M, Watson RS, Pediatric Acute Lung Injury C. The Outcomes of Children With Pediatric Acute Respiratory Distress Syndrome: Proceedings From the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2015; 16(5): 118-131. DOI:10.1097/PCC.0000000000000438.
Rodríguez Núñez A, López Herce J, del Castillo J, Bellón JM. Shockable rhythms and defibrillation during in-hospital pediatric cardiac arrest. Resuscitation. 2014; 85(3): 387-391. DOI:10.1016/j.resuscitation.2013.11.015.
Blanco L, Sanz B, Perez I, Sanchez CE, Luz Candenas M, Pinto FM, et al. Altered glutamyl-aminopeptidase activity and expression in renal neoplasms. BMC Cancer. 2014; 14. DOI:10.1186/1471-2407-14-386.
Larrinaga G, Perez I, Blanco L, Sanz B, Errarte P, Beitia M, et al. Prolyl Endopeptidase Activity Is Correlated with Colorectal Cancer Prognosis. Int J Med Sci. 2014; 11(2): 199-208. DOI:10.7150/ijms.7178.
Jordan Garcia I, Bustinza Arriourtua A, Concha Torre JA, Gil Anton J, de Carlos Vicente JC, Tellez Gonzalez C. A national multicentre study on nosocomial infections in PICU. An Pediatr. 2014; 80(1): 28-33. DOI:10.1016/j.anpedi.2010.09.010.
Gil Anton J, Lopez Bayon J, Lopez Fernandez Y, Morteruel E, Perez Estevez E, Lopez Herce J. Cardiac index monitoring by femoral arterial thermodilution after cardiac surgery in children. J Crit Care. 2014; 29(6). DOI:10.1016/j.jcrc.2014.06.004.
Astigarraga I, Echebarria A, Adan R, Garcia Ariza M, Lopez Almaraz R, Gil Anton J, et al. ONCOLOGIC EMERGENCIES THAT NEED INTENSIVE CARE AT DIAGNOSIS IN CHILDREN WITH CANCER. Pediatr Blood Cancer. 2014; 61(2): 391-391
Zarrazquin I, Torres Unda J, Ruiz F, Irazusta J, Kortajarena M, Hoyos Cillero I, et al. Longitudinal study: lifestyle and cardiovascular health in health science students. Nutr Hosp. 2014; 30(5): 1144-1151. DOI:10.3305/nh.2014.30.5.7833.
Lopez Herce J, del Castillo J, Canadas S, Rodriguez Nunez A, Carrillo A, Spanish Study Cardiopulm Arres GRP, et al. In-hospital Pediatric Cardiac Arrest in Spain. Rev Esp Cardiol. 2014; 67(3): 189-195. DOI:10.1016/j.rec.2013.07.017.
Lopez Herce J, del Castillo J, Matamoros M, Canadas S, Rodriguez Calvo A, Cecchetti C, et al. Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. Crit Care. 2014; 18(6). DOI:10.1186/s13054-014-0607-9.
GIL ANTON J, LOPEZ BAYON J, NIETO FAZA M, GARCIA URABAYEN D, LOPEZ FERNANDEZ YM, PEREZ ESTEVEZ E, et al. Introduction of high-fidelity simulation in Pediatric Basic Life Support training for medical students. Resuscitation. 2014
Gil-Anton J, Panez P, Saez F, Paniagua N, Romero A. Paradoxical air embolism after cardiac Computed tomography scan. Minerva Anestesiol. 2013;79:1093-4. FI: 2,818(Q2)
Mayordomo-Colunga J, Pons M, López Y, Solana MJ, Rey C, Martínez-Camblor P, et al. Predicting non-invasive ventilation failure in children from the SpO(2)/FiO(2) (SF) ratio. Intensive Care Med. 2013;39:1095-1103. FI: 5,258(Q1)
Larrinaga G, Sanz B, Blanco L, Perez I, Candenas ML, Pinto FM, et al. Cannabinoid CB1 receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma. Clin Biochem. 2013;46:638-41. FI: 2,450(Q1)
González Cortés R, Bustinza Arriortua A, Pons Ódena M, García Teresa MA, Cols Roig M, Gaboli M, et al. Ventilación mecánica domiciliaria en niños: estudio multicéntrico español. An Pediatr. 2013;78:227-33. FI: 0,867(Q3)
Gil-Anton J, Pavez P, Saez F, Paniagua N, Romero A. Paradoxical air embolism after cardiac Computed tomography scan. Minerva Anestesiol. 2013;-0. FI: 2,818(Q2)
Torres-Unda J, Zarrazquin I, Gil J, Ruiz F, Irazusta A, Kortajarena M, et al. Anthropometric, physiological and maturational characteristics in selected elite and non-elite male adolescent basketball players. J Sports Sci. 2013;31:196-203. FI: 2,082(Q2).
López-Herce J, Del Castillo J, Matamoros M, Cañadas S, Rodriguez-Calvo A, Cecchetti C, et al. Factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. Intensive Care Med. 2013;39:309-18. FI: 5,258(Q1)
Tesis del grupo
Autor/a: Yolanda Margarita López Fernández. Título: NA. Directores/as: Dra. Itziar Astigarraga Aguirre, Dr. Vicent Modesto i Alapont.
Autor/a: Javier Pilar Orive. Título: Identificación de un panel de marcadores proteicos en la fase inicial de la sepsis y su validación en una cohorte de pacientes pediátricos con sepsis grave. Director/as: Dras. Itziar Astigarraga y Susana García Obregón.
Autor/a: Aizpea Beatriz Echebarria Barona. Título: Implicación de los polimorfismos genéticos en la neurotoxicidad por Vincristina en pacientes pediátricos diagnosticados de Leucemia Linfoblástica Aguda. Director/a: Dra. Aurora Navajas Gutiérrez, Dra. África García-Orad Carles. UPV/EHU
Autor/a: Rafael Andrés Del Orbe Barreto. Título: Implementación de la Next Generation Sequencing en el diagnóstico de las Anemias Hemolíticas Congénitas. Director/a: Dra. Beatriz Arrizabalaga Amuchastegui, Dra. África García-Orad Carles. UPV/EHU
Autor/a: Nerea Bilbao Aldaiturriaga. Título: Variantes genéticas implicadas en la susceptibilidad del osteosarcoma pediátrico. Director/a: Dra. Idoia Martín Guerrero, Dra. África García-Orad Carles. UPV/EHU
Autor/a: María del Rosario Fátima González Hermosa. Título: Estudio prospectivo de las anomalías vasculares. Valoración del Propranolol en Hemangiomas. Director/a: Dra. Aurora Navajas Gutiérrez, Dra. María Dolores Boyano López,. UPV/EHU
Autor/a: María del Rosario Fátima González Hermosa. Título: Estudio prospectivo de las anomalías vasculares. Valoración del Propranolol en Hemangiomas. Director/a: Dra. Aurora Navajas Gutiérrez, Dra. María Dolores Boyano López,. UPV/EHU
