Medicina perinatal
Actividades del grupo
El Grupo de Investigación en Medicina Perinatal surge en el año 2021 tras la fusión de los grupos “Materno-fetal” y “Neonatología”, dada su habitual vinculación tanto clínica como en el área de investigación (integrados ambos en la antigua Red SAMID, Red de Salud materno Infantil y del Desarrollo, incluida desde 2022 dentro de uno de los programas RICORS, Primary care interventions to prevent maternal and Child chronic diseases of perinatal and development origin). Se mantienen tanto proyectos como líneas de investigación comunes, así como otras diferenciadas.
Dentro del campo de investigación en el área de Salud Materno-Fetal, que abarca desde la concepción de la gestación hasta el momento del parto, las líneas de trabajo se han centrado en áreas de especial trascendencia en la obstetricia actual:
- La primera línea de investigación se centra en la "Racionalización de la tasa de cesáreas". El aumento progresivo de las tasas de cesáreas mundiales requiere de estudios que aporten evidencia científica sobre los diferentes procedimientos que pueden invertir esta situación.
- La segunda línea se centra en la patología materno-fetal: trabajos sobre prematuridad, y la insuficiencia placentaria.
- Además, se está iniciando el desarrollo de un nuevo campo de investigación en Medicina Fetal con la creación de una unidad de terapia fetal, y colaborando en el estudio de nuevas herramientas de diagnóstico molecular no invasivo basadas en el análisis genético de células fetales aisladas de sangre materna, y el estudio sobre el diagnóstico prenatal de patologías oculares congénitas.
- Tenemos como objetivo primordial la mejora de la calidad de los cuidados que reciben las puérperas, así como los recién nacidos, especialmente aquellos identificados como recién nacidos prematuros tardíos. Entre nuestros objetivos también está la adecuación de la educación maternal a las necesidades de las mujeres y de la sociedad actual con el apoyo de las nuevas tecnologías para fomentar su autoconfianza y dotarla de autonomía para manejar su maternidad.
Dentro del campo de investigación en el área Neonatal, las líneas de trabajo se han centrado en áreas de especial trascendencia en la neonatología actual:
- Investigación epidemiológica en el área neonatal a nivel nacional e internacional. Promover una cultura de seguridad para los neonatos asistidos en las Unidades de Cuidados Intensivos Neonatales (UCINs), fundamentalmente previniendo la infección en los recién nacidos prematuros, especialmente las infecciones derivadas de la asistencia sanitaria.
- Desde 1991, se trabaja en el ámbito de la experimentación animal con diversas líneas de investigación relacionadas con patología pulmonar, neurológica y cardiovascular. Asimismo, la colaboración con los Dptos. de Biología Celular e Histología, la Escuela de Ingenieros y la Escuela Técnica Superior de Náutica ha permitido establecer las bases no solo para el desarrollo de dispositivos biomédicos, sino también para la validación de los mismos mediante los modelos experimentales animales antes mencionados.
- Generación de nuevo modelo de experimentación animal de Displasia Broncopulmonar.
- Por último, la Dra. B. Loureiro participa como investigadora colaboradora en un proyecto para estudiar las funciones ejecutivas en una muestra de prematuros de alto y bajo riesgo durante la adolescencia y adultez temprana, y realiza su tesis doctoral sobre el Seguimiento del Neurodesarrollo de los prematuros <1500g y/o < 32 semanas de la Unidad neonatal del HU Cruces durante 20 años.
La necesidad de adecuar la atención en salud a las necesidades de cada mujer, fomentar su autoconfianza y dotarla de autonomía para manejar su maternidad nos ha llevado a trabajar en el campo de la Educación Maternal; una actividad imprescindible en la capacitación de las mujeres para elegir y afrontar con responsabilidad su modelo de parto y crianza. Nuestro equipo de investigación lleva trabajando en este campo desde 2004 con diversos proyectos que se han ido encadenando, desde la evaluación de la educación maternal actual (Departamento de Sanidad del Gobierno Vasco. Expediente 200411004), pasando por el rediseño de una educación maternal centrada en la mujer (Servicio de Evaluación de Tecnologías Sanitarias. Proyecto comisionado. Expediente: 2009COM10), su modelado, implementación y evaluación (Instituto de Salud Carlos III. Expediente n◦ PI13/02632) y, actualmente estamos trabajando en la adecuación de la Educación Maternal a las nuevas tecnologías con dos proyectos, el desarrollo y evaluación de instrumentos de medición de necesidades en el embarazo, parto y puerperio (Departamento de Salud del Gobierno Vasco. Expediente: 2018111087) y la evaluación de la efectividad y usabilidad de una herramienta web EMAeHealth (Instituto de Salud Carlos III. Expediente n◦ PI20/00899) que contendría los instrumentos de medición de necesidades mencionados. Los resultados de estos proyectos han sido divulgados en publicaciones de ámbito nacional e internacional.
Coordinador/a del grupo
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Begoña Loureiro González
Coordinadora de grupo
begona.loureirogonzalez@osakidetza.eus
CV resumen -
Jorge Burgos San Cristóbal
Coordinador de grupo
jorge.burgossancristobal@osakidetza.eus
CV resumen
Miembros del grupo
Publicaciones del grupo
Martin Saiz L, Abad Garcia B, Solano Iturri JD, Mosteiro L, Martin Allende J, Rueda Y, et al. Using the Synergy between HPLC-MS and MALDI-MS Imaging to Explore the Lipidomics of Clear Cell Renal Cell Carcinoma. Anal Chem. 2023; 95(4): 2285-2293. DOI:10.1021/acs.analchem.2c03953.
Saffari A, Lau T, Tajsharghi H, Karimiani E, Kariminejad A, Efthymiou S, et al. The clinical and genetic spectrum of autosomal-recessive TOR1A-related disorders. Brain. 2023. DOI:10.1093/brain/awad039.
Rodriguez Lopez J, De la Cruz Bertolo J, Garcia Lara NR, Asla Elorriaga I, Roman Echevarria L, Vento M, et al. Maternal and Neonatal Prognostic Factors for Cardiorespiratory Events in Healthy Term Neonates During Early Skin-to-Skin Contact. Front Pediatr. 2022; 10: 907570-907570. DOI:10.3389/fped.2022.907570.
Maquibar A, Roman O, Belen Fraile Bermudez A, Estalella I. Achievements and challenges in baccalaureate student nurses' preparation for evidence-based nursing practice: A mixed methods study. J Prof Nurs. 2022; 40: 89-95. DOI:10.1016/j.profnurs.2022.03.008.
Molina F, Eliseo Blanco J, Burgos J, del Mar Gil M, Valladolid A, Pardo L, et al. Reliability and usability assessment of Fine Birth device for TPTL diagnosis. BJOG. 2022; 129: 19-19
Del Campo A, Aiartzaguena A, Suarez B, Rodriguez A, Rodriguez L, Burgos J. Lower uterine segment thickness assessed by ultrasound before labor induction: reproducibility analysis and relationship with clinical outcomes. Ultrasound Obstet Gynecol. 2022. DOI:10.1002/uog.26024.
Alana L, Martin Guerrero I, Navajas A, Zaldumbide L, Mosteiro L, Schwalbe EC, et al. MOLECULAR SUBCLASSIFICATION OF A NATIONAL COHORT OF PEDIATRIC MEDULLOBLASTOMA BASED ON METHYLATION PROFILE. Neuro-Oncology. 2022; 24: 121-121
Gomez Santos B, Fernamdez Puertas I, Nieva Zuluaga A, Ruiz de Gauna M, Apodaka Biguri M, Gonzalez Romero F, et al. The DNA damage response is involved in the metabolic dysregulation of MAFLD patients via inefficient fatty acid oxidation. J Hepatol. 2022; 77: 665-665
Gomez Pereira E, Burgos J, Mendoza R, Perez Ruiz I, Olaso F, Garcia D, et al. Endometriosis Increases the Risk of Placenta Previa in Both IVF Pregnancies and the General Obstetric Population. Reprod Sci. 2022. DOI:10.1007/s43032-022-01054-2.
Trilla C, Luna C, De Leon Socorro S, Rodriguez L, Ruiz Romero A, Mora Brugues J, et al. First-Trimester Sequential Screening for Preeclampsia Using Angiogenic Factors: Study Protocol for a Prospective, Multicenter, Real Clinical Setting Study. Front Cardiovasc Med. 2022; 9. DOI:10.3389/fcvm.2022.931943.
Fernandez de Gamarra Oca L, Ojeda N, Loureiro B, Sierra Ibarbia A, Garcia Guerrero MA, Pena J, et al. Maternal care and general cognitive functioning in moderate and late preterm-born children. Cogn Dev. 2022; 64. DOI:10.1016/j.cogdev.2022.101247.
Olive Cirera G, Martinez Gonzalez MJ, Armangue T. Pearls & Oy-sters: Tumefactive Demyelinating Lesions With MOG Antibodies Preceding Late-Infantile Metachromatic Leukodystrophy. Neurology. 2022; 99(19): 858-861. DOI:10.1212/WNL.0000000000201230.
Alba Pavon P, Alana L, Gutierrez Jimeno M, Echebarria Barona A, Imizcoz T, Zaldumbide L, et al. IDENTIFICATION OF POTENTIALLY PATHOGENIC VARIANTS IN CANCER PREDISPOSITION GENES IN PEDIATRIC SARCOMAS BY NEXT GENERATION SEQUENCING. Pediatr Blood Cancer. 2022; 69: 237-238
Lide A, Aguirre Carrillo JA, Martin Guerrero I, Zaldumbide L, Mosteiro L, Ansede Bermejo J, et al. NATIONAL EXPERIENCE AND USEFULNESS OF CENTRALIZED PATHOLOGICAL AND MOLECULAR REVIEW IN PEDIATRIC MEDULLOBLASTOMA. Pediatr Blood Cancer. 2022; 69: 301-302
Valletti MA, Furia F, Pisati A, Trivasano M, Ortigoza JD, Johanessen K, et al. Movement disorders as a part of the SCN8A-phenotypic spectrum. Epilepsia. 2022; 63: 202-202
Gomez Roig MD, Pascal R, Cahuana MJ, Garcia Algar O, Sebastiani G, Andreu Fernandez V et al. Environmental Exposure during Pregnancy: Influence on Prenatal Development and Early Life: A Comprehensive Review. Fetal Diagn Ther. 2021; 48(4): 1-13. DOI:10.1159/000514884.
Fernandez Pena A, Katsumiti A, De Basagoiti A, Castano M, Ros G, Sautua S et al. Drug compatibility in neonatal intensive care units: gaps in knowledge and discordances. Eur J Pediatr. 2021; 180(7): 2305-2313. DOI:10.1007/s00431-021-04028-9.
Loureiro B, De la Cruz Bertolo J, Blanco D, Ginovart G, Jimenez A, Martin Y et al. National protocol led to significant improvements in follow-up programmes for very low birth weight or very preterm infants. Acta Paediatr. 2021; 110(8): 2357-2358. DOI:10.1111/apa.15864.
Rey Santano C, Mielgo V, Gastiasoro E, Bianco F, Salomone F, Gomez Solaetxe MA. Surfactant nebulization therapy during NIPPV ventilation in surfactant-deficient newborn piglets. Pediatr Pulmonol. 2021; 56(7): 2125-2135. DOI:10.1002/ppul.25425.
Fernandez de Gamarra Oca L, Ojeda N, Gomez Gastiasoro A, Pena J, Ibarretxe Bilbao N, Garcia Guerrero MA et al. Long-Term Neurodevelopmental Outcomes after Moderate and Late Preterm Birth: A Systematic Review. J Pediatr. 2021; 237. DOI:10.1016/j.jpeds.2021.06.004.
Marina N, Lopez de Santa Maria E, Martinez A, Andia J, Iriberri M, Gonzalez N et al. A Web-based Application for Spirometry Quality in a Public Health System. 10 Year Follow Up. Arch Bronconeumol. 2021; 57(11): 724-725. DOI:10.1016/j.arbres.2021.04.026.
De Basagoiti A, Fernandez A, Mendiola S, De Miguel M, Guerra E, Loureiro B et al. Intravenous drug use in neonatal intensive care units. Eur J Hosp Pharm. 2021; 28(6): 341-345. DOI:10.1136/ejhpharm-2019-001939.
de las Heras J, Cano A, Vinuesa A, Montes M, Unceta Suarez M, Arza A et al. Importance of Timely Treatment Initiation in Infantile-Onset Pompe Disease, a Single-Centre Experience. Children (Basel). 2021; 8(11). DOI:10.3390/children8111026.
De Gamarra Oca LF, Zubiaurre Elorza L, Sierra Ibarbia A, Gomez Gastiasoro A, Loureiro B, Pena J et al. Parental bonding effects on cognitive outcomes after moderate and late preterm birth. Pediatr Res. 2021; 90(SUPPL 1): 3-3
Olabarri JD, Loureiro B, ASTIGARRAGA I, Guerra E, Echebarria Barona A, Adan R et al. Life-Threatening Complications at Diagnosis in Congenital Leukemia. Pediatr Blood Cancer. 2021; 68: 448-448
Delgado P, Robles Á, Martínez López JA, Sáez Comet L, Rodríguez Almaraz E, Martínez Sánchez N et al. Management of Pregnancy in Patients with Systemic Lupus Erythematosus/Antiphospholipid Syndrome. Part 3: Childbirth. Puerperium. Breastfeeding Contraception. Newborn. Reumatol Clin. 2021; 17(4): 183-186. DOI:10.1016/j.reuma.2019.09.004.
Espinosa G, Galindo Izquierdo M, Marcos Puig B, Casellas Caro M, Delgado Beltrán P, Martínez López JA et al. Pregnancy Control in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome. Part 1: Infertility, Ovarian Preservation and Preconception Assessment. Consensus Document of the Spanish Society of Gynaecology and Obstetrics (SEGO), the Spanish Society of Internal Medicine (SEMI) and the Spanish Society of Rheumatology (SER). Reumatol Clin. 2021; 17(2): 61-66. DOI:10.1016/j.reuma.2019.09.002.
Rodríguez Almaraz E, Sáez Comet L, Casellas M, Delgado P, Ugarte A, Vela Casasempere P et al. Pregnancy Control in Patients with Systemic Lupus Erythematosus/Antiphospholipid Syndrome: Part 2: Pregnancy Follow-Up. Reumatol Clin. 2021; 17(3): 125-131. DOI:10.1016/j.reuma.2019.09.003.
Gonzalez Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A et al. E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment. Cancer Res. 2021; 81(11): 2874-2887. DOI:10.1158/0008-5472.CAN-20-2052.
Peguero A, Herraiz I, Perales A, Melchor JC, Melchor I, Marcos B et al. Placental growth factor testing in the management of late preterm pre-eclampsia without severe features: A multi-center, randomized, controlled trial. Am J Obstet Gynecol. 2021; 225(3). DOI:10.1016/j.ajog.2021.03.044.
Llurba E, Bella M, Burgos J, Mazarico E, Gomez Roig MD, De Diego R et al. Early Prophylactic Enoxaparin for the Prevention of Preeclampsia and Intrauterine Growth Restriction: A Randomized Trial. Obstet Gynecol Surv. 2021; 76(3): 137-139
Matorras R, Valls R, Azkargorta M, Burgos J, Rabanal A, Elortza F et al. Proteomics based drug repositioning applied to improve in vitro fertilization implantation: an artificial intelligence model. Syst Biol Reprod Med. 2021; 67(4): 281-297. DOI:10.1080/19396368.2021.1928792.
Martin Saiz L, Mosteiro L, Solano Iturri JD, Rueda Y, Martin Allende J, Imaz I et al. High-Resolution Human Kidney Molecular Histology by Imaging Mass Spectrometry of Lipids. Anal Chem. 2021; 93(27): 9364-9372. DOI:10.1021/acs.analchem.1c00649.
Garcia Ruiz I, Sulleiro E, Serrano B, Fernandez Buhigas I, Rodriguez Gomez L, Sanchez Nieves D et al. Congenital infection of SARS-CoV-2 in live-born neonates: a population-based descriptive study. Clin Microbiol Infect. 2021; 27(10): 15211-15215. DOI:10.1016/j.cmi.2021.06.016.
Gonzalez Romero F, Mestre Congregado D, Aurrekoetxea I, Rourke CO, Andersen J, Woodhoo A et al. Repression of fatty acid oxidation in steatohepatitic-HCC is mediated by E2F1 and E2F2 transcription factors. J Hepatol. 2021; 75: 497-498
Aiartzaguena A, Del Campo A, Melchor I, Gutierrez J, Melchor JC, Burgos J. Expected-value bias in mid-trimester preterm birth screening. Ultrasound Obstet Gynecol. 2021; 59(6): 793-798. DOI:10.1002/uog.24778.
Alana Rodrigo L, Alba Pavon P, Bejarano OV, Duenas LZ, Gonzalez LM, Garcia AP et al. Usefulness of Next Generation Sequencing in the Diagnosis and Therapeutic Management of Pediatric Central Nervous System Tumors. Pediatr Blood Cancer. 2021; 68: 288-288
Gutierrez Jimeno M, Alba Pavon P, Imizcoz T, Echebarria Barona A, Alana L, Villate O et al. Genomic Characterization of Pediatric Bone Sarcomas by Next Generation Sequencing, Utility for Clinical Management. Pediatr Blood Cancer. 2021; 68: 250-250
Alana Rodrigo L, Nunes Xavier CE, Duenas LZ, Gonzalez LM, Guerrero IM, Garcia Obregon S et al. Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma. Pediatr Blood Cancer. 2021; 68: 289-289
Nunes Xavier CE, Zaldumbide L, Mosteiro L, Lopez Almaraz R, de Andoin NG, Aguirre P et al. Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets. Front Cell Dev Biol. 2021; 9: 811297-811297. DOI:10.3389/fcell.2021.811297.
Jimenez Marin A, Rivera D, Boado V, Diez I, Labayen F, Garrido I, et al. Brain connectivity and cognitive functioning in individuals six months after multiorgan failure. Neuroimage Clin. 2020; 25: 102137-102137. DOI:10.1016/j.nicl.2019.102137.
Mesa MD, Loureiro B, Iglesia I, Fernandez Gonzalez S, Llurba Olivé E, García Algar O, et al. The Evolving Microbiome from Pregnancy to Early Infancy: A Comprehensive Review. Nutrients. 2020; 12(1). DOI:10.3390/nu12010133.
Varela Barca L, Fernández Felix BM, Navas Elorza E, Mestres CA, Muñoz P, Cuerpo Caballero G, et al. Prognostic assessment of valvular surgery in active infective endocarditis: multicentric nationwide validation of a new score developed from a meta-analysis. Eur J Cardio-Thorac Surg. 2020; 57(4): 724-731. DOI:10.1093/ejcts/ezz328.
Villar J, Ferrando C, Martínez D, Ambrós A, Muñoz T, Soler JA, et al. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. Lancet Resp Med. 2020; 8(3): 267-276. DOI:10.1016/S2213-2600(19)30417-5.
Rey Santano C, Mielgo VE, Gomez Solaetxe MA, Bianco F, Salomone F, Loureiro B. Nebulized Poractant Alfa Reduces the Risk of Respiratory Failure at 72 Hours in Spontaneously Breathing Surfactant-Deficient Newborn Piglets. Crit Care Med. 2020; 48(6): 523-531. DOI:10.1097/CCM.0000000000004318.
Rey Santano C, Mielgo V, Gomez Solaetxe MA, Ricci F, Bianco F, Salomone F, et al. Dose-Response Study on Surfactant Nebulization Therapy During Nasal Continuous Positive Airway Pressure Ventilation in Spontaneously Breathing Surfactant-Deficient Newborn Piglets. Pediatr Crit Care Med. 2020; 21(7): 456-466. DOI:10.1097/PCC.0000000000002313.
Olaechea Astigarraga PM, Álvarez Lerma F, Beato Zambrano C, Gimeno Costa R, Gordo Vidal F, Durá Navarro R, et al. Epidemiology and prognosis of patients with a history of cancer admitted to intensive care. A multicenter observational study. Med Intensiv. 2020; 45(6): 332-346. DOI:10.1016/j.medin.2020.01.013.
Herrera Merchan A, Cuadros M, Rodriguez MI, Rodriguez S, Torres R, Estecio M, et al. The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma. Oncotarget. 2020; 11(13): 1172-1185
Agra Tuñas C, Rodriguez Ruiz E, Rodríguez Merino E, MOdos de Morir en UCI Pediátrica 2) study group of the Spanish S. How Do Children Die in PICUs Nowadays? A Multicenter Study From Spain. Pediatr Crit Care Med. 2020; 21(9): 610-616. DOI:10.1097/PCC.0000000000002359.
Boullosa Falces D, Garcia S, Sanz D, Trueba A, Angel Gomez Solaetxe M. CUSUM chart method for continuous monitoring of antifouling treatment of tubular heat exchangers in open-loop cooling seawater systems. Biofouling. 2020; 36(1): 73-85. DOI:10.1080/08927014.2020.1715954.
Galdiz JB, Gomez A, Rodriguez D, Guell R, Cebollero P, Hueto J, et al. Telerehabilitation Programme as a Maintenance Strategy for COPD Patients: A 12-Month Randomized Clinical Trial. Arch Bronconeumol. 2020; 57(3): 195-204. DOI:10.1016/j.arbres.2020.03.034.
Monte Armenteros J, Bereciartua Bastarrica E, Jimenez Maestre U, Guio Carrion L. [Bilateral pneumonia in a patient with Cushing's syndrome]. Rev Esp Quimioter. 2020; 33(4): 278-280. DOI:10.37201/req/001.2020.
Arnaez J, Herranz Rubia N, Garcia Alix A, Grupo de Trabajo E, Grupo de Trabajo ESP EHI. Atención integral del neonato con encefalopatía hipóxico-isquémica en España. An Pediatr. 2020; 92(5): 286-296. DOI:10.1016/j.anpedi.2019.05.013.
Rodriguez Garcia C, Barreiro Munoz E, Munoz Gall X, Bustamante Madariaga V, de Orive I, Javier Gonzalez Barcala F. Common errors in inhalation therapy: Impact and solutions. Clin Respir J. 2020; 14(11): 1001-1010. DOI:10.1111/crj.13236.
De Basagoiti A, Anton X, Calleja A, De Miguel M, Guerra E, Loureiro B, et al. Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units. Eur J Hosp Pharm. 2020; 29(1): 50-54. DOI:10.1136/ejhpharm-2019-002194.
Gil Anton J, Mielgo VE, Rey Santano C, Galbarriatu L, Santos C, Unceta M, et al. Addition of terlipressin to initial volume resuscitation in a pediatric model of hemorrhagic shock improves hemodynamics and cerebral perfusion. PLoS One. 2020; 15(7). DOI:10.1371/journal.pone.0235084.
Rey Santano C, Mielgo V, Salomone F, Bianco F, Gomez Solaetxe MA. The authors reply. Pediatr Crit Care Med. 2020; 21(10): 927-928. DOI:10.1097/PCC.0000000000002554.
De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, Lopez Gimenez LR, Pascual P, et al. Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units. Eur J Pediatr. 2020; 180(4): 1169-1176. DOI:10.1007/s00431-020-03854-7.
Colomer BF, Sanchez Luna M, Romero CD, Alarcon A, Souto AB, Longueira FC, et al. Neonatal Infection Due to SARS-CoV-2: An Epidemiological Study in Spain. Front Pediatr. 2020; 8. DOI:10.3389/fped.2020.580584.
Escudero Acha P, Leizaola O, Lazaro N, Cordero M, Cossio AM, Ballesteros D, et al. ADENI-UCI Study: Analysis of non-income decisions in ICU as a measure of limitation of life support treatments. Med Intensiv. 2020. DOI:10.1016/j.medin.2020.11.003.
Pericàs JM, Llopis J, Muñoz P, Gálvez Acebal J, Kestler M, Valerio M, et al. A Contemporary Picture of Enterococcal Endocarditis. J Am Coll Cardiol. 2020; 75(5): 482-494. DOI:10.1016/j.jacc.2019.11.047.
Gomez Larrauri A, Ortiz De Urbina B, Andia J, Garay E, Rezola A, Pedrero S, et al. Differences in the response to treatment with monoclonal antibodies according to age. Eur Resp J. 2020; 56. DOI:10.1183/13993003.congress-2020.2211.
Garcia Alix A, Arnaez J, Herranz Rubia N, Alarcon A, Arca G, Valverde E, et al. Ten years since the introduction of therapeutic hypothermia in neonates with perinatal hypoxic-ischaemic encephalopathy in Spain. Neurologia (Engl Ed). 2020. DOI:10.1016/j.nrl.2020.05.017.
Rodriguez L, Osuna C, Pijoan JI, Cobos P, Centeno MM, Serna R, et al. Patient opinion of analgesia during external cephalic version at term in singleton pregnancy. J Obstet Gynaecol. 2020; 40(6): 767-771. DOI:10.1080/01443615.2019.1647522.
Alzola I, Murua E, Rodríguez J, Burgos J, Maiz N. Can the Progression Angle before Labor Help to Predict Cesarean Section?. Fetal Diagn Ther. 2020; 47(4): 1-8. DOI:10.1159/000503387.
Cáliz R, Díaz Del Campo Fontecha P, Galindo Izquierdo M, López Longo FJ, Martínez Zamora MÁ, Santamaría Ortiz A, et al. Recommendations of the Spanish Rheumatology Society for Primary Antiphospholipid Syndrome. Part I: Diagnosis, Evaluation and Treatment. Reumatol Clin. 2020; 16(2 Pt 1): 71-86. DOI:10.1016/j.reuma.2018.11.003.
Cáliz R, Díaz Del Campo Fontecha P, Galindo Izquierdo M, López Longo FJ, Martínez Zamora MÁ, Santamaria Ortiz A, et al. Recommendations of the Spanish Rheumatology Society for Primary Antiphospholipid Syndrome. Part II: Obstetric Antiphospholipid Syndrome and Special Situations. Reumatol Clin. 2020; 16(2 Pt 2): 133-148. DOI:10.1016/j.reuma.2018.11.004.
Estalella I, San Millán J, Trincado MJ, Maquibar A, Martínez Indart L, San Sebastián M. Evaluation of an intervention supporting breastfeeding among late-preterm infants during in-hospital stay. WOMEN BIRTH. 2020; 33(1): 33-38. DOI:10.1016/j.wombi.2018.11.003.
Gil MM, Molina FS, Rodríguez Fernández M, Delgado JL, Carrillo MP, Jani J, et al. Risk of miscarriage after chorionic villus sampling. Ultrasound Obstet Gynecol. 2020. DOI:10.1002/uog.22041.
Villalaín C, Herraiz I, Valle L, Mendoza M, Delgado JL, Vázquez Fernández M, et al. Maternal and Perinatal Outcomes Associated With Extremely High Values for the sFlt-1 (Soluble fms-Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) Ratio. J Am Heart Assoc. 2020; 9(7). DOI:10.1161/JAHA.119.015548.
Rehal A, Benko Z, De Paco Matallana C, Syngelaki A, Janga D, Cicero S, et al. Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial. Am J Obstet Gynecol. 2020; 224(1): 861-8619. DOI:10.1016/j.ajog.2020.06.050.
Gomez Santos B, Saenz de Urturi D, Nunez Garcia M, Gonzalez Romero F, Buque X, Aurrekoetxea I, et al. Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. Aging Cell. 2020; 19(8): 13183-13183. DOI:10.1111/acel.13183.
Maiz N, Tajada M, Rodriguez MA, Irasarri A, Molina FS, Tubau A, et al. Three-dimensional ultrasonography for Advanced Neurosonography (NEUROSOFE-3D): Validation of a brain volume acquisition guideline. Acta Obstet Gynecol Scand. 2020; 100(1): 84-90. DOI:10.1111/aogs.13996.
Llurba E, Bella M, Burgos J, Mazarico E, Gomez Roig MD, De Diego R, et al. Early Prophylactic Enoxaparin for the Prevention of Preeclampsia and Intrauterine Growth Restriction: A Randomized Trial. Fetal Diagn Ther. 2020; 47(11): 824-833. DOI:10.1159/000509662.
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Tesis del grupo
Autor/a: Jaione San Millan de Clascá. Título: Diseño, implementación y evaluación de una intervención para el apoyo a la lactancia materna de los recién nacidos prematuros tardíos en la planta de maternidad del Hospital Universitario Cruces. Directores/as: Dra. Itziar Estalella Bellart, Fátima Ruiz Litago.
Autor/a: Irune Alzola Elizondo. Título: Predicción de la cesárea mediante una combinación de marcadores ecográficos y de historia clínica. Directores: Dr. Jorge Brugos San Cristobal.
