Laboratorio de Investigación en Inmunogenética - Immunogenetics Research Laboratory – IRLab

Gonzalez Moro I, Rojas Marquez H, Sebastian delaCruz M, Mentxaka Salgado J, Olazagoitia Garmendia A, Mendoza LM, et al. A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells. Front Endocrinol. 2023; 14: 1101934-1101934. DOI:10.3389/fendo.2023.1101934.

González García BP, Marí S, Cilleros Portet A, Hernangomez Laderas A, Fernandez Jimenez N, García Santisteban I, et al. Two-Sample Mendelian Randomization detects bidirectional causality between gut microbiota and celiac disease in individuals with high genetic risk. Front Immunol. 2023; 14. DOI:10.3389/fimmu.2023.1082862.

Gonzalez Moro I, Garcia Etxebarria K, Mendoza LM, Fernandez Jimenez N, Mentxaka J, Olazagoitia Garmendia A, et al. LncRNA ARGI Contributes to Virus-Induced Pancreatic ß Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes. Adv Sci. 2023; 10(25). DOI:10.1002/advs.202300063.

Soler Blasco R, Harari F, Riutort Mayol G, Murcia M, Lozano M, Irizar A, et al. Influence of genetic polymorphisms on arsenic methylation efficiency during pregnancy: Evidence from a Spanish birth cohort. Sci Total Environ. 2023; 900. DOI:10.1016/j.scitotenv.2023.165740.

Sebastian Delacruz M, Garcia Etxebarria K, Ramon Bilbao J, Lucendo AJ, Bujanda L, Castellanos Rubio A. A Novel, Noninvasive Method to Diagnose Active Eosinophilic Esophagitis, Combining Clinical Data and Oral Cavity RNA Levels. Clin Gastroenterol Hepatol. 2023. DOI:10.1016/j.cgh.2023.07.023.

Martinez Velasco S, Gonzalez Garcia A, Irastorza Terradillos IX, Bilbao Catala JR. Intestinal permeability assessment using lactulose and mannitol in celiac disease. METHOD CELL BIOL. 2023; 179: 39-50. DOI:10.1016/bs.mcb.2022.11.003.

Mendoza Gomez LM, Sebastian delaCruz M, Olazagoitia Garmendia A, Gonzalez Moro I, Rojas Marquez H, Mentxaka J, et al. Preparation of pepsin trypsin digested gliadin for stimulation experiments. METHOD CELL BIOL. 2023; 179: 195-201. DOI:10.1016/bs.mcb.2022.11.005.

Sebastian delaCruz M, Castellanos Rubio A. A fast, cheap, and easy protocol for celiac disease HLA haplotype typing using buccal swabs. METHOD CELL BIOL. 2023; 179: 203-212. DOI:10.1016/bs.mcb.2022.09.021.

Olazagoitia Garmendia A. Pepsin-trypsin digested gliadin treatment in intestinal cells. METHOD CELL BIOL. 2023; 179: 1-11. DOI:10.1016/bs.mcb.2022.11.002.

Romero MM, Serra D, Castellanos Rubio A, Herrero L. In vivo sensitization to gliadin by oral administration. METHOD CELL BIOL. 2023; 179: 51-57. DOI:10.1016/bs.mcb.2022.09.019.

Olazagoitia Garmendia A, Senovilla Ganzo R, Garcia Moreno F, Castellanos Rubio A. Functional evolutionary convergence of long noncoding RNAs involved in embryonic development. Commun Biol. 2023; 6(1): 908-908. DOI:10.1038/s42003-023-05278-z.

Beaumont RN, Flatley C, Vaudel M, Wu X, Chen J, Moen G, et al. Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genet. 2023. DOI:10.1038/s41588-023-01520-w.

Soler Blasco R, Llop S, Riutort Mayol G, Lozano M, Vallejo Ortega J, Murcia M, et al. Genetic Susceptibility to Neurotoxicity Related to Prenatal Inorganic Arsenic Exposure in Young Spanish Children. Environ Sci Technol. 2023; 57(41): 15366-15378. DOI:10.1021/acs.est.3c03336.

Badia Bringué G, Canive M, Fernandez Jimenez N, Lavín JL, Casais R, Blanco Vázquez C, et al. Summary-data based Mendelian randomization identifies gene expression regulatory polymorphisms associated with bovine paratuberculosis by modulation of the nuclear factor Kappa ß (NF-?ß)-mediated inflammatory response. BMC Genomics. 2023; 24(1): 605-605. DOI:10.1186/s12864-023-09710-w.

Beaumont RN, Flatley C, Vaudel M, Wu XP, Chen J, Moen GH, et al. Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genet. 2023. DOI:10.1038/s41588-023-01520.

Barreiro de Acosta M, Riestra S, Calafat M, Soto MP, Calvo M, Sanchez Rodriguez E, et al. Management and Long-term Outcomes of Crohn's Disease Complicated with Enterocutaneous Fistula: ECUFIT Study from GETECCU. J Crohns Colitis. 2022; 16(7): 1049-1058. DOI:10.1093/ecco-jcc/jjac016.

Galarreta Rodriguez I, Marcano L, Castellanos Rubio I, de Muro IG, Garcia I, Olivi L, et al. Towards the design of contrast-enhanced agents: systematic Ga3+ doping on magnetite nanoparticles. Dalton Trans. 2022; 51(6): 2517-2530. DOI:10.1039/d1dt03029a.

Gutierrez A, Zapater P, Ricart E, Gonzalez Vivo M, Gordillo J, Olivares D, et al. Immigrant IBD Patients in Spain Are Younger, Have More Extraintestinal Manifestations and Use More Biologics Than Native Patients. Front Med. 2022; 9: 823900-823900. DOI:10.3389/fmed.2022.823900.

Chaparro M, Baston Rey I, Fernandez Salgado E, Gonzalez Garcia J, Ramos L, Diz Lois Palomares MT, et al. Long-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn's Disease Patients: The SUSTAIN Study. Inflamm Bowel Dis. 2022. DOI:10.1093/ibd/izab357.

Perez Junkera G, Vazquez Polo M, Eizagirre FJ, Benjumea L, Tutau C, Esteban B, et al. Application of a Platform for Gluten-Free Diet Evaluation and Dietary Advice: From Theory to Practice. Sensors (Basel). 2022; 22(3). DOI:10.3390/s22030732.

Castellanos Rubio A, Ghosh S. Functional Implications of Intergenic GWAS SNPs in Immune-Related LncRNAs. AdvExpMedBiol. 2022; 1363: 147-160. DOI:10.1007/978-3-030-92034-0_8.

Sarzo B, Ballesteros V, Iniguez C, Manzano Salgado CB, Casas M, Llop S, et al. Response to "Comment on Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study: Predictability of Multiple Imputations for Large Amounts of Missing Data". Environ Sci Technol. 2022; 56(8): 5278-5282. DOI:10.1021/acs.est.2c01177.

Batista G, Marin Jimenez I, Fores A, Garcia Planella E, Arguelles Arias F, Tagarro I, et al. Treatment patterns and intensification within 5 year of follow-up of the first-line anti-TNF alpha used for the treatment of IBD: Results from the VERNE study. Dig Liver Dis. 2022; 54(1): 76-83. DOI:10.1016/j.dld.2021.06.005.

Garcia Etxebarria K, Merino O, Gaite Reguero A, Rodrigues PM, Herrarte A, Etxart A, et al. Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction. Sci Rep. 2022; 12(1): 3386-3386. DOI:10.1038/s41598-022-07401-2.

Rueda Martinez A, Gonzalez Garcia BP, Garitazelaia A, Cilleros Portet A, Mari S, Arauzo R, et al. Genetic basis of endometriosis in the susceptibility of developing gynecological cancers. Eur J Hum Genet. 2022; 30(SUPPL 1): 95-95

Cosin Tomas M, Cilleros Portet A, Aguilar Lacasana S, Fernandez Jimenez N, Bustamante M. Prenatal Maternal Smoke, DNA Methylation, and Multi-omics of Tissues and Child Health. Curr Environ Health Rep. 2022; 9(3): 502-512. DOI:10.1007/s40572-022-00361-9.

Cilleros Portet A, Mari S, Gonzalez Garcia BP, Garcia Santisteban I, Bustamante M, Marina LS, et al. Characterization of placental methylation quantitative trait loci. Eur J Hum Genet. 2022; 30(SUPPL 1): 554-554

Castellanos Rubio I, Baron A, Luis Lizarraga O, Rodrigo I, de Muro IG, Orue I, et al. Efficient Magneto-Luminescent Nanosystems based on Rhodamine-Loaded Magnetite Nanoparticles with Optimized Heating Power and Ideal Thermosensitive Fluorescence. ACS Appl Mater Interfaces. 2022; 14(44): 50033-50044. DOI:10.1021/acsami.2c14016.

Acosta MB, Fernandez Clotet A, Mesonero F, Garcia Alonso FJ, Casanova MJ, Fernandez de la Varga M, et al. Long-term outcomes of biological therapy in Crohn's disease complicated with internal fistulizing disease: BIOSCOPE study from GETECCU. Am J Gastroenterol. 2022. DOI:10.14309/ajg.0000000000002152.

Fernandez Jimenez N, Fore R, Cilleros Portet A, Lepeule J, Perron P, Kvist T, et al. A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health. Commun Biol. 2022; 5(1). DOI:10.1038/s42003-022-04267-y.

Casquero Veiga M, Lamanna Rama N, Romero Miguel D, Rojas Marquez H, Alcaide J, Beltran M, et al. The Poly I:C maternal immune stimulation model shows unique patterns of brain metabolism, morphometry, and plasticity in female rats. Front Behav Neurosci. 2023; 16: 1022622-1022622. DOI:10.3389/fnbeh.2022.1022622.

Garitazelaia A, Rueda Martinez A, Arauzo R, de Miguel J, Cilleros Portet A, Mari S et al. A Systematic Two-Sample Mendelian Randomization Analysis Identifies Shared Genetic Origin of Endometriosis and Associated Phenotypes. Life (Basel). 2021; 11(1). DOI:10.3390/life11010024.

Canive M, Fernandez Jimenez N, Casais R, Vazquez P, Lavin JL, Bilbao JR et al. Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression. Sci Rep. 2021; 11(1): 313-313. DOI:10.1038/s41598-020-79619-x.

Sebastian delaCruz M, Gonzalez Moro I, Olazagoitia Garmendia A, Castellanos Rubio A, Santin I. The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization. Non-coding RNA. 2021; 7(1). DOI:10.3390/ncrna7010003.

Olazagoitia Garmendia A, Zhang L, Mera P, Godbout JK, Sebastian delaCruz M, Garcia I et al. Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells. Gut. 2021; 71(1): 68-76. DOI:10.1136/gutjnl-2020-322566.

Bermejo F, Jimenez L, Algaba A, Vela M, Bastida G, Merino O et al. Re-induction With Intravenous Ustekinumab in Patients With Crohn's Disease and a Loss of Response to This Therapy. Inflamm Bowel Dis. 2021; 28(1): 41-47. DOI:10.1093/ibd/izab015.

Urrutia I, Martin Nieto A, Martinez R, Casanovas Marsal JO, Aguayo A, Del Olmo J et al. Incidence of diabetes mellitus and associated risk factors in the adult population of the Basque country, Spain. Sci Rep. 2021; 11(1): 3016-3016. DOI:10.1038/s41598-021-82548-y.

Garcia Santisteban I, Romero Garmendia I, Cilleros Portet A, Bilbao JR, Fernandez Jimenez N. Celiac disease susceptibility: The genome and beyond. Int Rev Cell Mol Biol. 2021; 358: 1-45. DOI:10.1016/bs.ircmb.2020.10.002.

Olazagoitia Garmendia A, Sebastian delaCruz M, Castellanos Rubio A. Involvement of lncRNAs in celiac disease pathogenesis. Int Rev Cell Mol Biol. 2021; 358: 241-264. DOI:10.1016/bs.ircmb.2020.10.004.

Garcia Santisteban I, Llopis A, Krenning L, Vallejo Rodriguez J, van den Broek B, Zubiaga AM et al. Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells. BMC Biol. 2021; 19(1). DOI:10.1186/s12915-021-00965-x.

Olazagoitia Garmendia A, Castellanos Rubio A. Relative Quantification of Residue-Specific m6A RNA Methylation Using m6A-RT-QPCR. Methods Mol Biol. 2021; 2298: 185-195. DOI:10.1007/978-1-0716-1374-0_12.

Sebastian delaCruz M, Olazagoitia Garmendia A, Madrigal AH, Garcia Etxebarria K, Mendoza LM, Fernandez Jimenez N et al. A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease. Cell Mol Gastroenterol Hepatol. 2021; 12(4). DOI:10.1016/j.jcmgh.2021.05.016.

Castellanos Rubio I, Arriortua O, Marcano L, Rodrigo I, Iglesias Rojas D, Baron A et al. Shaping Up Zn-Doped Magnetite Nanoparticles from Mono- and Bimetallic Oleates: The Impact of Zn Content, Fe Vacancies, and Morphology on Magnetic Hyperthermia Performance. Chem Mat. 2021; 33(9): 3139-3154. DOI:10.1021/acs.chemmater.0c04794.

Rueda Martinez A, Garitazelaia A, Cilleros Portet A, Mari S, Arauzo R, de Miguel J et al. Genetic Contribution of Endometriosis to the Risk of Developing Hormone-Related Cancers. Int J Mol Sci. 2021; 22(11). DOI:10.3390/ijms22116083.

Gonzalez Moro I, Sebastian delaCruz M, Rojas Marquez H, Olazagoitia Garmendia A, Mentxaka J, Mendoza LM et al. A long non-coding RNA that harbors a SNP associated with insulin levels regulates TGM2 gene expression in pancreatic beta cells. Diabetologia. 2021; 64(SUPPL 1): 8-9

Sarzo B, Ballesteros V, Iniguez C, Manzano Salgado CB, Casas M, Llop S et al. Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study. Environ Sci Technol. 2021; 55(16): 11144-11154. DOI:10.1021/acs.est.1c01452.

Everson TM, Vives Usano M, Seyve E, Cardenas A, Lacasana M, Craig JM et al. Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth. Nat Commun. 2021; 12(1). DOI:10.1038/s41467-021-24558-y.

Sainz E, Zabana Y, Miguel I, Fernandez Clotet A, Beltran B, Nunez L et al. Clinical features, therapeutic requirements and evolution of patients with Crohn's disease and upper gastrointestinal involvement (CROHNEX study). Aliment Pharmacol Ther. 2021; 54(8): 1041-1051. DOI:10.1111/apt.16547.

Sklias A, Halaburkova A, Vanzan L, Jimenez NF, Cuenin C, Bouaoun L et al. Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation. Nucleic Acids Res. 2021; 49(17): 9738-9754. DOI:10.1093/nar/gkab697.

Bermejo F, Jimenez L, Algaba A, Vela M, Bastida G, Merino O et al. Corrigendum to: Re-induction With Intravenous Ustekinumab in Patients With Crohn's Disease and a Loss of Response to This Therapy. Inflamm Bowel Dis. 2021; 28(1): 150-150. DOI:10.1093/ibd/izab242.

Olaechea Lazaro S, Garcia Santisteban I, Pineda JR, Badiola I, Alonso S, Bilbao JR et al. shinyCurves, a shiny web application to analyse multisource qPCR amplification data: a COVID-19 case study. BMC Bioinformatics. 2021; 22(1). DOI:10.1186/s12859-021-04392-1.

Canive M, Fernandez Jimenez N, Casais R, Vazquez P, Lavin JL, Bilbao JR et al. Author Correction: Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression. Sci Rep. 2021; 11(1): 21337-21337. DOI:10.1038/s41598-021-00840-3.

Calafat M, Manosa M, Ricart E, Nos P, Iglesias Flores E, Vera I et al. Risk of immunomediated adverse events and loss of response to infliximab in elderly patients with inflammatory bowel disease. A cohort study of the ENEIDA registry. J Crohns Colitis. 2021. DOI:10.1093/ecco-jcc/jjab213.

Deza DC, Calvo LJL, Mainar J, Ricart E, Gisbert JP, Tirado MR et al. Effectiveness and safety of ustekinumab in elderly patients: Real world evidence from ENEIDA registry. J Crohns Colitis. 2021; 15: 298-299. DOI:10.1093/ecco-jcc/jjab076.388.

Rodriguez Lago I, Fernandez Clotet A, Mesonero F, Garcia Alonso FJ, Casanova MJ, Fernandez de la Varga M et al. Long-term outcomes of biologic therapy in Crohn's disease complicated with internal fistulizing disease: BIOSCOPE study from GETECCU. J Crohns Colitis. 2021; 15: 377-378. DOI:10.1093/ecco-jcc/jjab076.481.

Ciria MM, Calafat M, Ricart E, Nos P, Iglesias E, Riestra S et al. Management and outcome of postoperative Crohn's Disease in the elderly as compared to young adults: Data from Eneida registry. J Crohns Colitis. 2021; 15: 69-70. DOI:10.1093/ecco-jcc/jjab073.070.

Garcia Romero R, Fernandez JMMD, Pujol Muncunill G, Donat Aliaga E, Segarra Canton O, Irastorza Terradillos I et al. Safety and effectiveness of vedolizumab in paediatric patients with inflammatory bowel disease: an observational multicentre Spanish study. Eur J Pediatr. 2021; 180(9): 3029-3038. DOI:10.1007/s00431-021-04063-6.

Rodriguez Lago I, Castro Poceiro J, Fernandez Clotet A, Mesonero F, Lopez Sanroman A, Lopez Garcia A, et al. Tacrolimus induces short-term but not long-term clinical response in inflammatory bowel disease. Aliment Pharmacol Ther. 2020; 51(9): 870-879. DOI:10.1111/apt.15687.

Rodriguez Lago I, Del Hoyo J, Casanova MJ, Fernandez Clotet A, Garcia MJ, Ferreiro Iglesias R, et al. Long-term effectiveness of anti-TNF agents in symptomatic stricturing Crohn's disease. J Crohns Colitis. 2020; 14: 467-468

Rodriguez Lago I, Merino O, Azagra I, Maiz A, Zapata E, Higuera R, et al. Risk of progression of preclinical ulcerative colitis. J Crohns Colitis. 2020; 14: 238-239

Aldaregia J, Errarte P, Olazagoitia Garmendia A, Gimeno M, Uriz JJ, Gershon TR, et al. Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma. Cancers (Basel). 2020; 12(4). DOI:10.3390/cancers12040997.

Agliata I, Fernandez Jimenez N, Goldsmith C, Marie JC, Bilbao JR, Dante R, et al. The DNA methylome of inflammatory bowel disease (IBD) reflects intrinsic and extrinsic factors in intestinal mucosal cells. Epigenetics. 2020; 15(10): 1-15. DOI:10.1080/15592294.2020.1748916.

Gonzalez Moro I, Olazagoitia Garmendia A, Colli ML, Cobo Vuilleumier N, Postler TS, Marselli L, et al. The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA. Proc Natl Acad Sci U S A. 2020; 117(16): 9022-9031. DOI:10.1073/pnas.1914353117.

Gonzalez Lamuno D, Irastorza I, Andrade F, Aldamiz Echevarria L. Vacuolated lymphocytes of blood smears in the diagnoses of lysosomal disorders. Mol Genet Metab. 2020; 129(2): 66-66. DOI:10.1016/j.ymgme.2019.11.154.

Gonzalez Lamuno D, Irastorza I, Andrade F, Gutierrez Larranaga M, San Segundo D, Aldamiz Echevarria L. Expression levels of the mono carboxylate transporter MCT1 in erythrocytes from patients with Fabry disease and predominant hypertrophic myocardiopathy. Mol Genet Metab. 2020; 129(2): 65-66. DOI:10.1016/j.ymgme.2019.11.153.

Rodriguez Lago I, Ramirez de la Piscina P, Elorza A, Merino O, Ortiz de Zarate J, Cabriada JL. Characteristics and prognosis of patients with inflammatory bowel disease during the SARS-CoV-2 pandemic in the Basque Country (Spain). Gastroenterology. 2020; 159(2): 781-783. DOI:10.1053/j.gastro.2020.04.043.

Marin Jimenez I, Bastida G, Forés A, Garcia Planella E, Argüelles Arias F, Sarasa P, et al. Impact of comorbidities on anti-TNFa response and relapse in patients with inflammatory bowel disease: the VERNE study. BMJ Open Gastroenterol. 2020; 7(1). DOI:10.1136/bmjgast-2019-000351.

Chaparro M, Garre A, Mesonero F, Rodriguez C, Barreiro de Acosta M, Martinez Cadilla J, et al. Tofacitinib in ulcerative colitis: Real-world evidence from Eneida Registry. J Crohns Colitis. 2020; 14: 26-28

Uribe Etxebarria V, Garcia Gallastegui P, Perez Garrastachu M, Casado Andres M, Irastorza I, Unda F, et al. Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells. Cells. 2020; 9(3). DOI:10.3390/cells9030652.

Koroknai V, Szasz I, Hernandez Vargas H, Fernandez Jimenez N, Cuenin C, Herceg Z, et al. DNA hypermethylation is associated with invasive phenotype of malignant melanoma. Exp Dermatol. 2020; 29(1): 39-50. DOI:10.1111/exd.14047.

Castellanos Rubio I, Rodrigo I, Olazagoitia Garmendia A, Arriortua O, Gil de Muro I, Garitaonandia JS, et al. Highly Reproducible Hyperthermia Response in Water, Agar and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles. ACS Appl Mater Interfaces. 2020; 12(25): 27917-27929. DOI:10.1021/acsami.0c03222.

Rodriguez Lago I, Ramirez C, Merino O, Azagra I, Maiz A, Zapata E, et al. Early microscopic findings in preclinical inflammatory bowel disease. Dig Liver Dis. 2020; 52(12): 1467-1472. DOI:10.1016/j.dld.2020.05.052.

Ruth N, Sharif K, Legarda M, Smith M, Lewis P, Lloyd C, et al. What is the long-term outlook for young people following liver transplant? A single-centre retrospective analysis of physical and psychosocial outcomes. Pediatr Transplant. 2020; 24(7): 13782-13782. DOI:10.1111/petr.13782.

Fernandez E, Cortazar A, Bellido V. Impact of covid-19 lockdown on glycemic control in patients with type 1 diabetes. Diabetes Res Clin Pract. 2020; 166: 108348-108348. DOI:10.1016/j.diabres.2020.108348.

Rodriguez Lago I, Hoyo JD, Perez Girbes A, Garrido Marin A, Casanova MJ, Chaparro M, et al. Early treatment with anti-tumor necrosis factor agents improves long-term effectiveness in symptomatic stricturing Crohn's disease. United European Gastroenterol J. 2020; 8(9): 1056-1066. DOI:10.1177/2050640620947579.

Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, et al. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet. 2020; 16(10): 1008718-1008718. DOI:10.1371/journal.pgen.1008718.

Vandriel S, Li LT, She HY, Wang JS, Gilbert MA, Spinner NB, et al. PHENOTYPIC DIVERGENCE OF JAGGED1 AND NOTCH2-ASSOCIATED ALAGILLE SYNDROME: RESULTS FROM THE INTERNATIONAL MULTICENTER GALA STUDY GROUP. Hepatology. 2020; 72: 882-884

Sebastian delaCruz M, Olazagoitia Garmendia A, Gonzalez Moro I, Santin I, Garcia Etxebarria K, Castellanos Rubio A. Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease. Epigenomes. 2020; 4(3). DOI:10.3390/epigenomes4030016.

Roa Esparza I, Gonzalez Ocio J, Merino Ochoa O. Acute gastric dilatation in a patient with anorexia nervosa. Rev Esp Enferm Dig. 2020; 113(4): 302-302. DOI:10.17235/reed.2020.7235/2020.

Garcia Santisteban I, Cilleros Portet A, Moyua E, Kurilshikov A, Zhernakova A, Garcia Etxebarria K, et al. Causal effects of gut microbiota on celiac disease: a two-sample mendelian randomization approach. Eur J Hum Genet. 2020; 28(SUPPL 1): 707-707

Gonzalez Moro I, Olazagoitia Garmendia A, Colli ML, Cobo Vuilleumier N, Postler TS, Marselli L, et al. The T1D-associated lncRNA Lnc13 modulates human pancreatic ss-cell inflammation by allele-specific stabilization of STAT1 mRNA. Eur J Hum Genet. 2020; 28(SUPPL 1): 998-998

Olazagoitia Garmendia A, Zhang L, Mera P, Irastorza I, Serra D, Herrero L, et al. SNP rs3087898 located next to m6A motif influences gluten-induced RNA methylation changes that regulate intestinal inflammation via allele-specific XPO1 translation. Eur J Hum Genet. 2020; 28(SUPPL 1): 757-758

Zenarruzabeitia O, Vitallé J, Terrén I, Orrantia A, Astigarraga I, Dopazo L, et al. CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow's milk allergy. J Allergy Clin Immunol. 2019; 143(2): 700-7115. DOI:10.1016/j.jaci.2018.05.022.

Fernandez Jimenez N, Garcia Etxebarria K, Plaza Izurieta L, Romero Garmendia I, Jauregi Miguel A, Legarda M, et al. The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. Sci Rep. 2019; 9(1): 1298-1298. DOI:10.1038/s41598-018-37746-6.

Dos Santos RS, Marroqui L, Velayos T, Olazagoitia Garmendia A, Jauregi Miguel A, Castellanos Rubio A, et al. DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway. Diabetologia. 2019; 62(3): 459-472. DOI:10.1007/s00125-018-4782-0.

Middeldorp CM, Felix JF, Mahajan A, EArly Genetics Lifecourse Epidemiology (EAGLE) C, Early Growth Genetics (EGG) C, McCarthy MI. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. Eur J Epidemiol. 2019; 34(3): 279-300. DOI:10.1007/s10654-019-00502-9.

Rodriguez Lago I, Castro Poceiro J, Fernandez Clotet A, Mesonero F, Lopez Sanroman A, Lopez Garcia A, et al. Efficacy and safety of tacrolimus in Crohn's disease: a nationwide, multi-centric study from GETECCU. J Crohns Colitis. 2019; 13(1): 207-208. DOI:10.1093/ecco-jcc/jjy222.347.

Rodriguez Lago I, Castro Poceiro J, Fernandez Clotet A, Mesonero F, Lopez Sanroman A, Lopez Garcia A, et al. Efficacy and safety of tacrolimus in ulcerative colitis: a nationwide, multi-centre study from GETECCU. J Crohns Colitis. 2019; 13(1): 52-53. DOI:10.1093/ecco-jcc/jjy222.078.

Rodríguez Lago I, Merino O, López de Goicoechea MJ, Aranzamendi M, Zubiaurre L, Muro N, et al. Immunosuppression for inflammatory bowel disease does not influence Epstein-Barr viral load in the short-term. Gastroenterol Hepatol. 2019; 42(9): 542-547. DOI:10.1016/j.gastrohep.2019.03.016.

Cielo D, Galatola M, Fernandez Jimenez N, De Leo L, Garcia Etxebarria K, Loganes C, et al. Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients' Signatures. Sci Rep. 2019; 9. DOI:10.1038/s41598-019-46468-2.

Castellanos Rubio A, Santin I, Olazagoitia Garmendia A, Romero Garmendia I, Jauregi Miguel A, Legarda M, et al. A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation. Sci Rep. 2019; 9. DOI:10.1038/s41598-019-40018-6.

Castellanos Rubio A, Ghosh S. Disease-Associated SNPs in Inflammation-Related lncRNAs. Front Immunol. 2019; 10: 420-420. DOI:10.3389/fimmu.2019.00420.

Ochoa E, Zuber V, Fernandez Jimenez N, Bilbao JR, Clark GR, Maher ER, et al. MethylCal: Bayesian calibration of methylation levels. Nucleic Acids Res. 2019; 47(14). DOI:10.1093/nar/gkz325.

Romero Garmendia I, Fernandez Jimenez N, Garcia Etxebarria K, Jauregi Miguel A, Olazagoitia Garmendia A, Santin I, et al. Where SNPs, coexpression and TADs intersect: new insights in the regulation of coexpression in celiac disease. Eur J Hum Genet. 2019; 27(1): 606-607

Fernandez Jimenez N, Romero Garmendia I, Garcia Etxebarria K, Jauregi Miguel A, Irastorza I, Bilbao JR. TAP1 and HLA-B genes in the HLA region are hypomethylated and overexpressed in celiac duodenal cell populations. Eur J Hum Genet. 2019; 27(1): 608-608

Fernandez Jimenez N, Ramon Bilbao J. Mendelian randomization analysis of celiac GWAS reveals a blood expression signature with diagnostic potential in absence of gluten consumption. Hum Mol Genet. 2019; 28(18): 3037-3042. DOI:10.1093/hmg/ddz113.

Patil V, Cuenin C, Chung F, Aguilera JRR, Fernandez Jimenez N, Romero Garmendia I, et al. Human mitochondrial DNA is extensively methylated in a non-CpG context. Nucleic Acids Res. 2019; 47(19): 10072-10085. DOI:10.1093/nar/gkz762.

Sanchez C, Hernani MT, Alvarez Calatayud G, Miranda Cid C, Manuel Navas V, Marin Jimenez I, et al. Status of transition care in inflammatory bowel disease in Spain. Different medical perspectives. Rev Esp Enferm Dig. 2019; 111(11): 833-838. DOI:10.17235/reed.2019.6310/2019.

Ochoa E, Zuber V, Fernandez Jimenez N, Bilbao JR, Clark G, Maher ER, et al. MethylCal: Bayesian calibration of methylation levels. Eur J Hum Genet. 2019; 27(2): 1648-1648

Fernandez Jimenez N, Bilbao JR. Mendelian Randomization analysis of celiac GWAS reveals a blood expression signature with diagnostic potential in absence of gluten consumption. Eur J Hum Genet. 2019; 27(2): 1708-1708

Olazagoitia Garmendia A, Rodriguez J, Bilbao J, Castellanos Rubio A. An inflammation-related SNP in XPO1 5 ` UTR regulates protein amount by altering m6A mRNA methylation. Eur J Hum Genet. 2019; 27(1): 627-627

Rudilla F, Franco Jarava C, Martínez Gallo M, Garcia Prat M, Martín Nalda A, Rivière J, et al. Expanding the Clinical and Genetic Spectra of Primary Immunodeficiency-Related Disorders With Clinical Exome Sequencing: Expected and Unexpected Findings. Front Immunol. 2019; 10: 2325-2325. DOI:10.3389/fimmu.2019.02325.

Castellanos Rubio A, Bilbao JR. Profiling Celiac Disease-Related Transcriptional Changes. Int Rev Cell Mol Biol. 2018; 336: 149-174. DOI:10.1016/bs.ircmb.2017.07.003.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, et al. DNA methylation in childhood asthma: an epigenome-wide meta-analysis. Lancet Resp Med. 2018; 6(5): 379-388. DOI:10.1016/S2213-2600(18)30052-3.

Santin I, Jauregi Miguel A, Velayos T, Castellanos Rubio A, Garcia Etxebarria K, Romero Garmendia I, et al. Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells. J Pediatr Gastroenterol Nutr. 2018; 67(2): 225-231. DOI:10.1097/MPG.0000000000001970.

Muñoz Villafranca C, Ortiz de Zarate J, Arreba P, Higuera R, Gómez L, Ibáñez S, et al. Adalimumab treatment of anti-TNF-naïve patients with ulcerative colitis: Deep remission and response factors. Dig Liver Dis. 2018; 50(8): 812-819. DOI:10.1016/j.dld.2018.03.007.

Romero Garmendia I, Garcia Etxebarria K, Hernandez Vargas H, Santin I, Jauregi Miguel A, Plaza Izurieta L, et al. Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease. Genes. 2018; 9(5). DOI:10.3390/genes9050245.

Olazagoitia Garrnendia A, Santin I, Castellanos Rubio A. Functional implication of celiac disease associated lncRNAs in disease pathogenesis. Comput Biol Med. 2018; 102: 369-375. DOI:10.1016/j.compbiomed.2018.08.013.

Nunez C, Garrote JA, S. Recommendations to report and interpret HLA genetic findings in coeliac disease. Rev Esp Enferm Dig. 2018; 110(7): 458-461. DOI:10.17235/reed.2018.5269/2017.

Romero Garmendia I, Jauregi Miguel A, Santin I, Bilbao JR, Castellanos Rubio A. Subcellular Fractionation from Fresh and Frozen Gastrointestinal Specimens. J Vis Exp. 2018. DOI:10.3791/57740.

Taxonera C, Ponferrada A, Riestra S, Bermejo F, Saro C, Martin Arranz MD, et al. Serial Tuberculin Skin Tests Improve the Detection of Latent Tuberculosis Infection in Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2018; 12(11): 1270-1279. DOI:10.1093/ecco-jcc/jjy104.

Barreiro de Acosta M, Marin Jimenez I, Panadero A, Guardiola J, Canas M, Montoya MG, et al. Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) and the Association of Crohn's Disease and Ulcerative Colitis Patients (ACCU) in the management of psychological problems in Inflammatory Bowel Disease patients. Gastroenterol Hepatol. 2018; 41(2): 118-127. DOI:10.1016/j.gastrohep.2017.10.003.

Knip M, Akerblom HK, Al Taji E, Becker D, Bruining J, Castano L, et al. Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes The TRIGR Randomized Clinical Trial. JAMA-J Am Med Assoc. 2018; 319(1): 38-48. DOI:10.1001/jama.2017.19826.

Marquez A, Kerick M, Zhernakova A, Gutierrez Achury J, Chen W, Onengut Gumuscu S, et al. Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations. Genome Med. 2018; 10. DOI:10.1186/s13073-018-0604-8.

Woo HD, Fernandez Jimenez N, Ghantous A, Degli Esposti D, Cuenin C, Cahais V, et al. Genome-wide profiling of normal gastric mucosa identifies Helicobacter pylori- and cancer-associated DNA methylome changes. Int J Cancer. 2018; 143(3): 597-609. DOI:10.1002/ijc.31381.

Casanova MJ, Chaparro M, García Sánchez V, Nantes O, Leo E, Rojas Feria M, et al. Evolution After Anti-TNF Discontinuation in Patients With Inflammatory Bowel Disease: A Multicenter Long-Term Follow-Up Study. Am J Gastroenterol. 2017; 112(1): 120-131. DOI:10.1038/ajg.2016.569.

Velayos T, Martínez R, Alonso M, Garcia Etxebarria K, Aguayo A, Camarero C, et al. An Activating Mutation in STAT3 Results in Neonatal Diabetes Through Reduced Insulin Synthesis. Diabetes. 2017; 66(4): 1022-1029. DOI:10.2337/db16-0867.

Urrutia I, Martínez R, López Euba T, Velayos T, Martínez de LaPiscina I, Bilbao JR, et al. Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY. PLoS One. 2017; 12(1). DOI:10.1371/journal.pone.0169389.

Smarrazzo A, Misak Z, Costa S, Micetic Turk D, Abu Zekry M, Kansu A, et al. Diagnosis of celiac disease and applicability of ESPGHAN guidelines in Mediterranean countries: a real life prospective study. BMC Gastroenterol. 2017; 17(1): 17-17. DOI:10.1186/s12876-017-0577-x.

Signes Pastor AJ, Vioque J, Navarrete Muñoz EM, Carey M, García de la Hera M, Sunyer J, et al. Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain. Environ Res. 2017; 159: 69-75. DOI:10.1016/j.envres.2017.07.046.

Santin I, Dos Santos RS, Marroqui L, Castellanos Rubio A, Velayos T, Jauregi Miguel A, et al. The type 1 diabetes candidate gene DEXI modulates virus-induced beta cell dysfunction via regulation of type I interferons. Diabetologia. 2017; 60(1): 204-205

Castellanos Rubio A, Kratchmarov R, Sebastian M, Garcia Etxebarria K, Garcia L, Irastorza I, et al. Cytoplasmic Form of Carlr lncRNA Facilitates Inflammatory Gene Expression upon NF-kappa B Activation. J Immunol. 2017; 199(2): 581-588. DOI:10.4049/jimmunol.1700023.

Ordas I, Domenech E, Manosa M, Garcia Sanchez V, Iglesias Flores E, Penalva M, et al. Long-Term Efficacy and Safety of Cyclosporine in a Cohort of Steroid-Refractory Acute Severe Ulcerative Colitis Patients from the ENEIDA Registry (1989-2013): A Nationwide Multicenter Study. Am J Gastroenterol. 2017; 112(11): 1709-1718. DOI:10.1038/ajg.2017.180.

Smarrazzo A, Magazzu G, Ben Hariz M, Tamara ML, Velmishi V, Roma E, et al. Variability of anti-human transglutaminase testing in celiac disease across Mediterranean countries. World J Gastroenterol. 2017; 23(24): 4437-4443. DOI:10.3748/wjg.v23.i24.4437.

Giner CP, Vendrell MCM, Martinez RG, Lopez LG, Munoz PG, Terradillos II, et al. Pediatric parenteral nutrition: clinical practice guidelines from the Spanish Society of Parenteral and Enteral Nutrition (SENPE), the Spanish Society of Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP) and the Spanish Society of Hospital Pharmacy (SEFH). Nutr Hosp. 2017; 34(3): 745-758. DOI:10.20960/nh.1116.

Benitez JM, Barreiro de Acosta M, Chaparro M, Vazquez JM, Iglesias Flores E, Tosca J, et al. Evolution after a "de-intensification" strategy with anti-TNF therapy in patients with inflammatory bowel disease in clinical remission: multicenter study. J Crohns Colitis. 2017; 11(1): 243-243

Chaparro M, Verreth A, Lobaton T, Gravito Soares E, Julsgaard M, Savarino E, et al. Long-term safety of in utero exposure to anti-tumor necrosis factor for the treatment of inflammatory bowel diseases: results from the multicenter European TEDDY study. J Crohns Colitis. 2017; 11(1): 34-35. DOI:10.1093/ecco-jcc/jjx002.053.

Ordas I, Domenech E, Aguas M, Fernandez Banares F, Garcia S, Penalva M, et al. Post-operative mortality and predictive factors in a cohort of severe refractory ulcerative colitis patients from the ENEIDA Registry (1989-2013): a multicenter nationwide study. J Crohns Colitis. 2017; 11(1): 389-389

Taxonera C, Ponferrada A, Bermejo F, Gisbert JP, Riestra S, Saro C, et al. Serial tuberculin skin test improves the detection of latent tuberculosis infection in inflammatory bowel disease patients. J Crohns Colitis. 2017; 11(1): 63-63

Escudero Hernandez C, Plaza Izurieta L, Garrote JA, Ramon Bilbao J, Arranz E, C. Association of the IL-15 and IL-15R alpha genes with celiac disease. Cytokine. 2017; 99: 73-79. DOI:10.1016/j.cyto.2017.07.009.

Tentelier C, Barroso Gomila O, Lepais O, Manicki A, Romero Garmendia I, Jugo BM. Testing mate choice and overdominance at MH in natural families of Atlantic salmon Salmo salar. J Fish Biol. 2017; 90(4): 1644-1659. DOI:10.1111/jfb.13260.

Irastorza Terradillos I. Vías de acceso en nutrición parenteral pediátrica. Nutr Hosp. 2017; 34(Suppl 3): 9-13

Moreno Villare JM, Irastorza Terradillos I, Prieto Bozano G. Complicaciones de la nutrición parenteral pediátrica. Nutr Hosp. 2017; 34(Suppl 3): 55-61

Esposti DD, Sklias A, Lima SC, Divonne SBD, Cahais V, Fernandez Jimenez N, et al. Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas. Genome Med. 2017; 9. DOI:10.1186/s13073-017-0419-z.

Castellanos Rubio I, Insausti M, de Muro IG, Arias Duque DC, Hernandez Garrido JC, Lezama L. Intra-particle chemical homogeneity determining the exchange coupling in palladium-iron nanoparticles. J Appl Phys. 2017; 121(8). DOI:10.1063/1.4976966.

Rodriguez Lago I, Merino O, Nantes O, Munoz C, Aguirre U, Luis Cabriada J, et al. Previous exposure to biologics and C-reactive protein are associated with the response to tacrolimus in inflammatory bowel disease. Rev Esp Enferm Dig. 2016; 108(9): 550-557. DOI:10.17235/reed.2016.4447/2016.

Castellanos Rubio A, Fernandez Jimenez N, Kratchmarov R, Luo X, Bhagat G, Green PHR, et al. A long noncoding RNA associated with susceptibility to celiac disease. Science. 2016; 352(6281): 91-95. DOI:10.1126/science.aad0467.

Taxonera C, Barreiro Acosta M, Bastida G, Martinez Gonzalez J, Merino O, Garcia Sanchez V, et al. Outcomes of Medical and Surgical Therapy for Entero-urinary Fistulas in Crohn's Disease. J Crohns Colitis. 2016; 10(6): 657-662. DOI:10.1093/ecco-jcc/jjw016.

Pichler J, Biassoni L, Easty M, Irastorza I, Hill S. Reduced risk of pulmonary emboli in children treated with long-term parenteral nutrition. Clin Nutr. 2016; 35(6): 1406-1413. DOI:10.1016/j.clnu.2016.03.016.

R Grau Mdel C, Chaparro M, Mesonero F, Barreiro de Acosta M, Castro L, Castro M, et al. Effectiveness of anti-TNF alpha drugs in patients with Crohn's disease who do not achieve remission with their first anti-TNF alpha agent. Dig Liver Dis. 2016; 48(6): 613-619. DOI:10.1016/j.dld.2016.02.012.

Garcia Etxebarria K, Jauregi Miguel A, Romero Garmendia I, Plaza Izurieta L, Legarda M, Irastorza I, et al. Ancestry-based stratified analysis of Immunochip data identifies novel associations with celiac disease. Eur J Hum Genet. 2016; 24(12): 1831-1834. DOI:10.1038/ejhg.2016.120.

Garcia Etxebarria K, Jauregi Miguel A, Romero Garmendia I, Plaza Izurieta L, Legarda M, Irastorza I, et al. Ancestry-based stratified analysis of Immunochip data identifies novel associations with celiac disease. Eur J Hum Genet. 2016; 24(12): 1831-1834. DOI:10.1038/ejhg.2016.120.

Chavarria Herbozo C, Casanova MJ, Barreiro de Acosta M, Chaparro M, Ezquiaga E, Bujanda L, et al. Prevalence and factors associated with fatigue in patients with inflammatory bowel disease: a multicentre study. J Crohns Colitis. 2016; 10(1): 432-433

Casanova M, Chaparro M, Molina B, Merino O, Nuevo Siguairo O, Duenas Sadornil C, et al. Prevalence of malnutrition and nutritional characteristics of patients with inflammatory bowel disease. J Crohns Colitis. 2016; 10(1): 208-209

Rodriguez Lago I, Merino O, Lopez de Goicoechea MJ, Aranzamendi M, Zubiaurre L, Ortiz de Zarate J, et al. Immunosuppression for inflammatory bowel disease does not affect Epstein-Barr viral load in the short-term: preliminary results. J Crohns Colitis. 2016; 10(1): 491-491

Castellanos Rubio I, Insausti M, de Muro IG, Rojo T, Lezama L. Tuning the Size of Palladium Nanoparticles in Organic and Aqueous Solutions: Influence of Aminated and Thiolated Ligands. J Nanosci Nanotechnol. 2016; 16(4): 4071-4079. DOI:10.1166/jnn.2016.11711.

Casanova MJ, Chaparro M, Garcia Sanchez V, Nantes O, Jauregui Amezaga A, Rojas Feria M, et al. Evolution after anti-TNF drug discontinuation in patients with inflammatory bowel disease (IBD): a multicenter long-term follow-up study. J Crohns Colitis. 2015; 9(1): 329-329

Rodriguez Lago I, Merino O, Nantes O, Moraleja I, Cabriada JL. Long - term efficacy of Tacrolimus in Inflammatory Bowel Disease: a retrospective pilot study. J Crohns Colitis. 2015; 9(1): 354-354

Taxonera C, Ponferrada A, Gisbert JP, Bermejo F, Martinez Arranz MD, de Castro ML, et al. Performance of Tuberculin skin test in routine screening for latent tuberculosis infection in patients with inflammatory bowel diseases. J Crohns Colitis. 2015; 9(1): 197-198

Villafranca CM, Higuera R, Merino O, Nantes O, de la Piscina PR, Munagorri A, et al. Adalimumab treatment in Ulcerative Colitis patients who are naive to anti-TNF: Week 8 of our pilot study. J Crohns Colitis. 2015; 9(1): 249-249

Plaza Izurieta L, Fernandez Jimenez N, Irastorza I, Jauregi Miguel A, Romero Garmendia I, Carlos Vitoria J, et al. Expression analysis in intestinal mucosa reveals complex relations among genes under the association peaks in celiac disease. Eur J Hum Genet. 2015; 23(8): 1100-1105. DOI:10.1038/ejhg.2014.244.

Plaza Izurieta L, Fernandez Jimenez N, Irastorza I, Jauregi Miguel A, Romero Garmendia I, Carlos Vitoria J, et al. Expression analysis in intestinal mucosa reveals complex relations among genes under the association peaks in celiac disease. Eur J Hum Genet. 2015; 23(8): 1100-1105. DOI:10.1038/ejhg.2014.244.

Gordillo J, Cabre E, Garcia Planella E, Ricart E, Ber Nieto Y, Marquez L, et al. Thiopurine Therapy Reduces the Incidence of Colorectal Neoplasia in Patients with Ulcerative Colitis. Data from the ENEIDA Registry. J Crohns Colitis. 2015; 9(12): 1063-1070. DOI:10.1093/ecco-jcc/jjv145.

Fernandez Jimenez N, Castellanos Rubio A, Plaza Izurieta L, Irastorza I, Elcoroaristizabal X, Jauregi Miguel A, et al. Coregulation and modulation of NF kappa B-related genes in celiac disease: uncovered aspects of gut mucosal inflammation. Hum Mol Genet. 2014; 23(5): 1298-1310. DOI:10.1093/hmg/ddt520.

Fernandez Jimenez N, Castellanos Rubio A, Plaza Izurieta L, Irastorza I, Elcoroaristizabal X, Jauregi Miguel A, et al. Coregulation and modulation of NF kappa B-related genes in celiac disease: uncovered aspects of gut mucosal inflammation. Hum Mol Genet. 2014; 23(5): 1298-1310. DOI:10.1093/hmg/ddt520.

Axpe E, Lopez Euba T, Castellanos Rubio A, Merida D, Garcia JA, Plaza Izurieta L, et al. Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy. PLoS One. 2014; 9(1). DOI:10.1371/journal.pone.0083838.

Bondar C, Plaza Izurieta L, Fernandez Jimenez N, Irastorza I, Withoff S, Wijmenga C, et al. THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge. Eur J Hum Genet. 2014; 22(3): 358-362. DOI:10.1038/ejhg.2013.136.

Bondar C, Plaza Izurieta L, Fernandez Jimenez N, Irastorza I, Withoff S, Wijmenga C, et al. THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge. Eur J Hum Genet. 2014; 22(3): 358-362. DOI:10.1038/ejhg.2013.136.

Tucci F, Astarita L, Abkari A, Abu Zekry M, Attard T, Ben Hariz M, et al. Celiac disease in the Mediterranean area. BMC Gastroenterol. 2014; 14. DOI:10.1186/1471-230X-14-24.

Tucci F, Astarita L, Abkari A, Abu Zekry M, Attard T, Ben Hariz M, et al. Celiac disease in the Mediterranean area. BMC Gastroenterol. 2014; 14. DOI:10.1186/1471-230X-14-24.

Romanos J, Rosen A, Kumar V, Trynka G, Franke L, Szperl A, et al. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut. 2014; 63(3): 415-422. DOI:10.1136/gutjnl-2012-304110.

Jauregi Miguel A, Fernandez Jimenez N, Irastorza I, Plaza Izurieta L, Carlos Vitoria J, Ramon Bilbao J. Alteration of Tight Junction Gene Expression in Celiac Disease. J Pediatr Gastroenterol Nutr. 2014; 58(6): 762-767. DOI:10.1097/MPG.0000000000000338.

Jauregi Miguel A, Fernandez Jimenez N, Irastorza I, Plaza Izurieta L, Carlos Vitoria J, Ramon Bilbao J. Alteration of Tight Junction Gene Expression in Celiac Disease. J Pediatr Gastroenterol Nutr. 2014; 58(6): 762-767. DOI:10.1097/MPG.0000000000000338.

Almeida R, Ricano Ponce I, Kumar V, Deelen P, Szperl A, Trynka G, et al. Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Hum Mol Genet. 2014; 23(9): 2481-2489. DOI:10.1093/hmg/ddt619.

Irastorza I, Tutau C, Carlos Vitoria J. A trichobezoar in a child with undiagnosed celiac disease: A case report. World J Gastroenterol. 2014; 20(5): 1357-1360. DOI:10.3748/wjg.v20.i5.1357.

Knip M, Åkerblom HK, Becker D, Dosch HM, Dupre J, Fraser W, et al. Hydrolyzed Infant Formula and Early beta-Cell Autoimmunity A Randomized Clinical Trial. JAMA-J Am Med Assoc. 2014; 311(22): 2279-2287. DOI:10.1001/jama.2014.5610.

Martin Guerrero I, de Prado E, Lopez E, Ardanaz M, Carlos Vitoria J, Parada LA, et al. Methylation of the nonhomologous end joining repair pathway genes does not explain the increase of translocations with aging. Age. 2014; 36(6). DOI:10.1007/s11357-014-9730-4.

Canas Ventura A, Marquez L, Ricart E, Domenech E, Gisbert JP, Garcia Sanchez V, et al. Risk of colectomy in patients with ulcerative colitis under thiopurine treatment. J Crohns Colitis. 2014; 8(10): 1287-1293. DOI:10.1016/j.crohns.2014.03.014.

Vitoria JC,  Bilbao JR. Updates on coeliac disease. An Pediatr. 2013;78:1-5. FI: 0,867(Q3)